NPFFR1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NPFFR1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NPFFR1 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0032870Biological processcellular response to hormone stimulus
GO_0008150Biological processbiological_process
GO_0005929Cellular componentcilium
GO_0005886Cellular componentplasma membrane
GO_0042277Molecular functionpeptide binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0008188Molecular functionneuropeptide receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNPFFR1
Protein nameNeuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide-related peptide receptor OT7T022)
SynonymsNPFF1
GPR147
DescriptionFUNCTION: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

AccessionsENST00000277942.7
Q9GZQ6