GPR65 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	35 studies	39% ± 11%	Explore
CD8-positive, alpha-beta T cell	22 studies	25% ± 7%	Explore
mast cell	20 studies	42% ± 14%	Explore
mature NK T cell	17 studies	36% ± 8%	Explore
T cell	16 studies	22% ± 6%	Explore
mucosal invariant T cell	15 studies	37% ± 12%	Explore
CD4-positive, alpha-beta T cell	15 studies	22% ± 4%	Explore
gamma-delta T cell	15 studies	31% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	38% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	36% ± 11%	Explore
non-classical monocyte	11 studies	27% ± 9%	Explore
macrophage	11 studies	22% ± 3%	Explore
plasmacytoid dendritic cell	11 studies	35% ± 15%	Explore
conventional dendritic cell	9 studies	23% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	29% ± 10%	Explore
classical monocyte	8 studies	22% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	25% ± 8%	Explore
monocyte	8 studies	21% ± 9%	Explore
innate lymphoid cell	7 studies	38% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	21% ± 8%	Explore
B cell	5 studies	16% ± 1%	Explore
myeloid cell	5 studies	24% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	20% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	21% ± 8%	Explore
leukocyte	4 studies	24% ± 4%	Explore
CD4-positive helper T cell	4 studies	24% ± 8%	Explore
neutrophil	3 studies	20% ± 4%	Explore
mononuclear phagocyte	3 studies	26% ± 5%	Explore
memory B cell	3 studies	22% ± 3%	Explore
microglial cell	3 studies	28% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	25% ± 7%	Explore
granulocyte	3 studies	51% ± 10%	Explore
dendritic cell	3 studies	42% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 13%	Explore
T-helper 17 cell	3 studies	36% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	29% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	552.49	578 / 578	83%	3.08	955 / 1155
breast	88%	101.69	404 / 459	93%	4.11	1040 / 1118
kidney	85%	123.35	76 / 89	84%	4.43	754 / 901
stomach	89%	96.66	318 / 359	69%	2.08	197 / 286
intestine	90%	199.15	869 / 966	60%	1.56	316 / 527
uterus	87%	89.39	148 / 170	61%	1.50	279 / 459
prostate	96%	163.16	235 / 245	42%	0.78	210 / 502
thymus	76%	86.18	497 / 653	57%	1.58	343 / 605
bladder	81%	156.38	17 / 21	52%	1.51	260 / 504
esophagus	82%	107.36	1180 / 1445	49%	1.10	89 / 183
liver	90%	106.77	204 / 226	33%	0.75	135 / 406
adrenal gland	97%	148.02	250 / 258	26%	0.46	60 / 230
pancreas	36%	31.11	119 / 328	79%	2.56	141 / 178
skin	41%	41.49	739 / 1809	63%	2.78	297 / 472
lymph node	0%	0	0 / 0	100%	10.45	29 / 29
spleen	100%	1387.77	241 / 241	0%	0	0 / 0
peripheral blood	100%	1166.35	928 / 929	0%	0	0 / 0
brain	34%	43.95	904 / 2642	65%	3.60	458 / 705
ovary	28%	18.93	51 / 180	69%	1.95	296 / 430
adipose	97%	187.60	1167 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	80%	2.61	36 / 45
blood vessel	64%	92.61	851 / 1335	0%	0	0 / 0
heart	48%	38.85	413 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	9%	0.19	7 / 80
muscle	3%	1.93	26 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0006955	Biological process	immune response
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0035025	Biological process	positive regulation of Rho protein signal transduction
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0090630	Biological process	activation of GTPase activity
GO_0051496	Biological process	positive regulation of stress fiber assembly
GO_0010447	Biological process	response to acidic pH
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005886	Cellular component	plasma membrane
GO_0004930	Molecular function	G protein-coupled receptor activity

IV. Literature review

[source]

Gene name	GPR65
Protein name	Psychosine receptor (G-protein coupled receptor 65) (T-cell death-associated gene 8 protein) G protein-coupled receptor 65 (Orphan GPCR 65)
Synonyms	hCG_1642415 TDAG8
Description	FUNCTION: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids . Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance . May have a role in activation-induced cell death or differentiation of T-cells (By similarity). .
Accessions	B5B0C2 Q8IYL9 ENST00000267549.5

GPR65 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review