GPR132 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPR132 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0010972Biological processnegative regulation of G2/M transition of mitotic cell cycle
GO_0000082Biological processG1/S transition of mitotic cell cycle
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameGPR132
Protein nameG protein-coupled receptor 132
Truncated G protein-coupled receptor 132
Probable G-protein coupled receptor 132 (G2 accumulation protein)
SynonymsG2A
DescriptionFUNCTION: May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity. .

AccessionsB2LM89
ENST00000329797.8 [Q9UNW8-1]
ENST00000392585.2 [Q9UNW8-3]
ENST00000551869.1
F8VRH8
ENST00000549990.1
ENST00000539291.6 [Q9UNW8-1]
A0A0G2JL29
Q9UNW8