S1PR5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of S1PR5 at tissue level.

III. Associated gene sets

GO_0045664Biological processregulation of neuron differentiation
GO_0003376Biological processsphingosine-1-phosphate receptor signaling pathway
GO_0019222Biological processregulation of metabolic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0038036Molecular functionsphingosine-1-phosphate receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameS1PR5
Protein nameAlternative protein S1PR5
Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8)
Sphingosine-1-phosphate receptor 5
SynonymsEDG8
DescriptionFUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. .

AccessionsQ9H228
L8ECK7
K7EIT5
ENST00000333430.6 [Q9H228-1]
ENST00000439028.3 [Q9H228-1]
ENST00000590601.1