Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 27 studies | 37% ± 14% | |
CD16-positive, CD56-dim natural killer cell, human | 13 studies | 49% ± 10% | |
mature NK T cell | 11 studies | 30% ± 7% | |
CD16-negative, CD56-bright natural killer cell, human | 8 studies | 28% ± 11% | |
gamma-delta T cell | 7 studies | 25% ± 8% | |
CD8-positive, alpha-beta T cell | 6 studies | 24% ± 6% | |
mucosal invariant T cell | 5 studies | 20% ± 3% | |
oligodendrocyte | 3 studies | 17% ± 1% | |
effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 3 studies | 25% ± 7% |
Insufficient scRNA-seq data for expression of S1PR5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 90% | 1215.21 | 2380 / 2642 | 76% | 8.55 | 536 / 705 |
bladder | 48% | 208.48 | 10 / 21 | 63% | 13.81 | 318 / 504 |
lung | 60% | 254.94 | 344 / 578 | 47% | 10.48 | 540 / 1155 |
skin | 72% | 976.31 | 1309 / 1809 | 28% | 1.76 | 132 / 472 |
spleen | 100% | 1067.36 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 41.40 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.84 | 1 / 1 |
esophagus | 38% | 422.89 | 551 / 1445 | 58% | 14.54 | 107 / 183 |
prostate | 60% | 228.02 | 146 / 245 | 36% | 1.57 | 182 / 502 |
uterus | 2% | 21.51 | 4 / 170 | 77% | 29.03 | 354 / 459 |
peripheral blood | 71% | 2231.15 | 660 / 929 | 0% | 0 | 0 / 0 |
pancreas | 13% | 26.97 | 42 / 328 | 43% | 3.06 | 76 / 178 |
kidney | 3% | 5.81 | 3 / 89 | 51% | 3.14 | 457 / 901 |
breast | 10% | 23.51 | 48 / 459 | 39% | 2.05 | 434 / 1118 |
adrenal gland | 1% | 1.33 | 2 / 258 | 34% | 1.75 | 78 / 230 |
lymph node | 0% | 0 | 0 / 0 | 31% | 0.81 | 9 / 29 |
liver | 12% | 29.12 | 27 / 226 | 12% | 0.49 | 47 / 406 |
thymus | 6% | 12.57 | 40 / 653 | 16% | 0.90 | 97 / 605 |
intestine | 1% | 2.39 | 11 / 966 | 9% | 0.46 | 48 / 527 |
stomach | 0% | 0.45 | 1 / 359 | 9% | 0.30 | 26 / 286 |
adipose | 9% | 20.59 | 103 / 1204 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 7% | 0.55 | 30 / 430 |
blood vessel | 4% | 8.60 | 47 / 1335 | 0% | 0 | 0 / 0 |
heart | 1% | 3.06 | 12 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045664 | Biological process | regulation of neuron differentiation |
GO_0003376 | Biological process | sphingosine-1-phosphate receptor signaling pathway |
GO_0019222 | Biological process | regulation of metabolic process |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0038036 | Molecular function | sphingosine-1-phosphate receptor activity |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | S1PR5 |
Protein name | Alternative protein S1PR5 Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8) Sphingosine-1-phosphate receptor 5 |
Synonyms | EDG8 |
Description | FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. . |
Accessions | Q9H228 L8ECK7 K7EIT5 ENST00000333430.6 [Q9H228-1] ENST00000439028.3 [Q9H228-1] ENST00000590601.1 |