MRGPRD report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MRGPRD at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MRGPRD at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameMRGPRD
Protein nameMas-related G-protein coupled receptor member D (Beta-alanine receptor) (G-protein coupled receptor TGR7)
SynonymsMRGD
DescriptionFUNCTION: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

AccessionsENST00000309106.3
Q8TDS7