GPR173 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0097211Biological processcellular response to gonadotropin-releasing hormone
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_2001223Biological processnegative regulation of neuron migration
GO_0005886Cellular componentplasma membrane
GO_0004968Molecular functiongonadotropin-releasing hormone receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameGPR173
Protein nameG protein-coupled receptor 173
Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3)
SynonymsSREB3
DescriptionFUNCTION: Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth . .

AccessionsQ9NS66
J3KPD1
ENST00000332582.5
ENST00000375466.2