S1PR2 | OmnibusX

Name	Number of supported studies	Average coverage
fibroblast	5 studies	26% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of S1PR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	1120.87	1806 / 1809	100%	37.48	472 / 472
breast	100%	1019.85	458 / 459	100%	14.82	1115 / 1118
lung	100%	2469.01	578 / 578	99%	14.63	1139 / 1155
ovary	99%	953.36	178 / 180	98%	13.23	420 / 430
uterus	99%	1476.32	169 / 170	97%	15.49	445 / 459
prostate	100%	1279.87	245 / 245	95%	7.29	479 / 502
bladder	100%	1454.33	21 / 21	95%	11.02	480 / 504
thymus	98%	650.64	643 / 653	94%	13.03	569 / 605
esophagus	98%	888.63	1419 / 1445	89%	6.86	162 / 183
intestine	99%	792.40	956 / 966	88%	7.09	462 / 527
stomach	95%	629.90	340 / 359	88%	9.01	253 / 286
adrenal gland	95%	415.26	246 / 258	80%	6.96	185 / 230
pancreas	77%	258.81	251 / 328	99%	13.37	176 / 178
liver	84%	496.46	190 / 226	84%	11.46	343 / 406
kidney	73%	312.07	65 / 89	70%	4.76	633 / 901
brain	21%	52.76	568 / 2642	96%	12.05	676 / 705
eye	0%	0	0 / 0	100%	12.62	80 / 80
lymph node	0%	0	0 / 0	100%	48.24	29 / 29
tonsil	0%	0	0 / 0	100%	11.96	45 / 45
ureter	0%	0	0 / 0	100%	6.74	1 / 1
adipose	100%	1210.51	1203 / 1204	0%	0	0 / 0
heart	94%	675.18	812 / 861	0%	0	0 / 0
spleen	92%	320.06	222 / 241	0%	0	0 / 0
blood vessel	83%	405.13	1108 / 1335	0%	0	0 / 0
peripheral blood	35%	551.17	326 / 929	0%	0	0 / 0
muscle	8%	22.55	61 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_1903142	Biological process	positive regulation of establishment of endothelial barrier
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0030036	Biological process	actin cytoskeleton organization
GO_0003376	Biological process	sphingosine-1-phosphate receptor signaling pathway
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0090394	Biological process	negative regulation of excitatory postsynaptic potential
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0046847	Biological process	filopodium assembly
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0010800	Biological process	positive regulation of peptidyl-threonine phosphorylation
GO_0019222	Biological process	regulation of metabolic process
GO_0005886	Cellular component	plasma membrane
GO_0098794	Cellular component	postsynapse
GO_0005737	Cellular component	cytoplasm
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0008289	Molecular function	lipid binding
GO_0005178	Molecular function	integrin binding
GO_0001664	Molecular function	G protein-coupled receptor binding
GO_0008528	Molecular function	G protein-coupled peptide receptor activity
GO_0038036	Molecular function	sphingosine-1-phosphate receptor activity
GO_0005515	Molecular function	protein binding

Gene name	S1PR2
Protein name	Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5)
Synonyms	EDG5
Description	FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) . S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues . When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis . Receptor for the chemokine-like protein FAM19A5 . Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity). .
Accessions	O95136 ENST00000646641.1

S1PR2 report