TAS2R4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAS2R4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAS2R4 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0001580Biological processdetection of chemical stimulus involved in sensory perception of bitter taste
GO_0007585Biological processrespiratory gaseous exchange by respiratory system
GO_0060170Cellular componentciliary membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0008527Molecular functiontaste receptor activity
GO_0033038Molecular functionbitter taste receptor activity

IV. Literature review

[source]
Gene nameTAS2R4
Protein nameTaste receptor type 2 member 4 (T2R4)
Taste receptor type 2
Synonymstcag7.328
DescriptionFUNCTION: Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. .

AccessionsA4D1U1
Q9NYW5
A1L485
ENST00000247881.4