MTNR1B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of MTNR1B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	37%	2.83	979 / 2642	1%	0.03	8 / 705
bladder	19%	0.48	4 / 21	6%	0.29	30 / 504
skin	23%	0.97	412 / 1809	0%	0.00	1 / 472
pancreas	18%	0.54	59 / 328	1%	0.04	2 / 178
uterus	14%	0.34	23 / 170	3%	0.21	14 / 459
liver	4%	0.11	10 / 226	7%	0.99	30 / 406
stomach	9%	0.23	33 / 359	0%	0	0 / 286
prostate	9%	0.28	21 / 245	0%	0.00	1 / 502
breast	7%	0.23	31 / 459	2%	0.08	21 / 1118
adrenal gland	6%	0.14	16 / 258	1%	0.03	2 / 230
ovary	7%	0.29	12 / 180	0%	0	0 / 430
lung	5%	0.13	28 / 578	1%	0.02	10 / 1155
kidney	4%	0.11	4 / 89	1%	0.04	5 / 901
esophagus	4%	0.10	60 / 1445	1%	0.04	1 / 183
intestine	4%	0.10	38 / 966	0%	0.00	1 / 527
thymus	4%	0.10	26 / 653	0%	0	0 / 605
peripheral blood	4%	0.11	35 / 929	0%	0	0 / 0
spleen	4%	0.08	9 / 241	0%	0	0 / 0
muscle	3%	0.09	27 / 803	0%	0	0 / 0
adipose	3%	0.07	36 / 1204	0%	0	0 / 0
blood vessel	3%	0.07	39 / 1335	0%	0	0 / 0
heart	3%	0.07	25 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.03	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0050796	Biological process	regulation of insulin secretion
GO_0010754	Biological process	negative regulation of cGMP-mediated signaling
GO_0051970	Biological process	negative regulation of transmission of nerve impulse
GO_0046676	Biological process	negative regulation of insulin secretion
GO_0051971	Biological process	positive regulation of transmission of nerve impulse
GO_0098908	Biological process	regulation of neuronal action potential
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0007268	Biological process	chemical synaptic transmission
GO_0046010	Biological process	positive regulation of circadian sleep/wake cycle, non-REM sleep
GO_0007187	Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0045906	Biological process	negative regulation of vasoconstriction
GO_0043010	Biological process	camera-type eye development
GO_0043524	Biological process	negative regulation of neuron apoptotic process
GO_0042593	Biological process	glucose homeostasis
GO_0051481	Biological process	negative regulation of cytosolic calcium ion concentration
GO_0005886	Cellular component	plasma membrane
GO_0045202	Cellular component	synapse
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0008502	Molecular function	melatonin receptor activity
GO_0005515	Molecular function	protein binding

Gene name	MTNR1B
Protein name	Melatonin receptor MEL1B Melatonin receptor 1B variant b Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Melatonin receptor 1B
Synonyms
Description	FUNCTION: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Accessions	Q8TEV7 H0YDG4 E9PR36 Q7Z583 ENST00000528076.1 ENST00000532482.1 ENST00000257068.3 P49286

MTNR1B report