NPBWR2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NPBWR2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NPBWR2 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0038003Biological processG protein-coupled opioid receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0043005Cellular componentneuron projection
GO_0016020Cellular componentmembrane
GO_0042923Molecular functionneuropeptide binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0008188Molecular functionneuropeptide receptor activity
GO_0005515Molecular functionprotein binding
GO_0004985Molecular functionG protein-coupled opioid receptor activity

IV. Literature review

[source]
Gene nameNPBWR2
Protein nameNeuropeptides B/W receptor 2
Neuropeptides B/W receptor type 2 (G-protein coupled receptor 8)
SynonymsGPR8
DescriptionFUNCTION: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.

AccessionsENST00000612646.2
ENST00000369768.1
ENST00000684052.1
P48146
Q6NWQ5