HCAR1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HCAR1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HCAR1 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0050995Biological processnegative regulation of lipid catabolic process
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameHCAR1
Protein nameHydroxycarboxylic acid receptor 1
Hydroxycarboxylic acid receptor 1 (G-protein coupled receptor 104) (G-protein coupled receptor 81)
SynonymsFKSG80
GPR104
GPR81
HCA1
DescriptionFUNCTION: Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway. .

AccessionsENST00000432564.3
A0A4Y1JWP1
Q9BXC0