Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 14 studies | 22% ± 8% | |
naive B cell | 13 studies | 26% ± 6% | |
memory B cell | 12 studies | 26% ± 7% | |
T follicular helper cell | 3 studies | 28% ± 8% |
Insufficient scRNA-seq data for expression of CXCR5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
spleen | 100% | 222.59 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 54.73 | 885 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 8.02 | 26 / 29 |
blood vessel | 62% | 4.47 | 827 / 1335 | 0% | 0 | 0 / 0 |
intestine | 52% | 31.69 | 500 / 966 | 2% | 0.11 | 10 / 527 |
lung | 50% | 3.28 | 291 / 578 | 2% | 0.06 | 28 / 1155 |
bladder | 43% | 2.81 | 9 / 21 | 1% | 0.03 | 4 / 504 |
adipose | 33% | 2.04 | 401 / 1204 | 0% | 0 | 0 / 0 |
prostate | 33% | 2.00 | 80 / 245 | 1% | 0.01 | 3 / 502 |
breast | 29% | 1.63 | 135 / 459 | 2% | 0.05 | 19 / 1118 |
stomach | 25% | 1.71 | 91 / 359 | 4% | 0.15 | 11 / 286 |
esophagus | 27% | 1.76 | 394 / 1445 | 1% | 0.02 | 1 / 183 |
thymus | 23% | 4.06 | 149 / 653 | 2% | 0.04 | 14 / 605 |
skin | 18% | 0.82 | 331 / 1809 | 6% | 0.15 | 27 / 472 |
muscle | 20% | 1.02 | 164 / 803 | 0% | 0 | 0 / 0 |
uterus | 20% | 0.92 | 34 / 170 | 0% | 0.00 | 1 / 459 |
pancreas | 15% | 0.58 | 50 / 328 | 4% | 0.13 | 8 / 178 |
ovary | 18% | 0.87 | 32 / 180 | 0% | 0 | 0 / 430 |
kidney | 16% | 2.30 | 14 / 89 | 0% | 0.00 | 1 / 901 |
liver | 11% | 0.45 | 24 / 226 | 0% | 0.01 | 2 / 406 |
tonsil | 0% | 0 | 0 / 0 | 11% | 0.15 | 5 / 45 |
heart | 10% | 0.51 | 84 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 9% | 0.39 | 23 / 258 | 0% | 0 | 0 / 230 |
brain | 4% | 0.18 | 118 / 2642 | 0% | 0.01 | 2 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006955 | Biological process | immune response |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0070098 | Biological process | chemokine-mediated signaling pathway |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0030595 | Biological process | leukocyte chemotaxis |
GO_0019722 | Biological process | calcium-mediated signaling |
GO_0042113 | Biological process | B cell activation |
GO_0032467 | Biological process | positive regulation of cytokinesis |
GO_0060326 | Biological process | cell chemotaxis |
GO_0048535 | Biological process | lymph node development |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016493 | Molecular function | C-C chemokine receptor activity |
GO_0019957 | Molecular function | C-C chemokine binding |
GO_0016494 | Molecular function | C-X-C chemokine receptor activity |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CXCR5 |
Protein name | Chemokine (C-X-C motif) receptor 5 C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185) |
Synonyms | MDR15 BLR1 |
Description | FUNCTION: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
Accessions | Q2YD84 ENST00000292174.5 [P32302-1] P32302 |