CXCR5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CXCR5 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0030595Biological processleukocyte chemotaxis
GO_0019722Biological processcalcium-mediated signaling
GO_0042113Biological processB cell activation
GO_0032467Biological processpositive regulation of cytokinesis
GO_0060326Biological processcell chemotaxis
GO_0048535Biological processlymph node development
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016493Molecular functionC-C chemokine receptor activity
GO_0019957Molecular functionC-C chemokine binding
GO_0016494Molecular functionC-X-C chemokine receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCXCR5
Protein nameChemokine (C-X-C motif) receptor 5
C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
SynonymsMDR15
BLR1
DescriptionFUNCTION: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

AccessionsQ2YD84
ENST00000292174.5 [P32302-1]
P32302