MC2R report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MC2R at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MC2R at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0019222Biological processregulation of metabolic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004977Molecular functionmelanocortin receptor activity
GO_0004978Molecular functioncorticotropin receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMC2R
Protein nameAdrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R) (Adrenocorticotropin receptor) (Melanocortin receptor 2) (MC2-R)
Adrenocorticotropic hormone receptor (Adrenocorticotropin receptor) (Melanocortin receptor 2)
SynonymsACTHR
DescriptionFUNCTION: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). .

FUNCTION: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). .

AccessionsENST00000399821.2
ENST00000327606.4
Q01718
R4GMM0