GPR17 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPR17 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0035025Biological processpositive regulation of Rho protein signal transduction
GO_0002862Biological processnegative regulation of inflammatory response to antigenic stimulus
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0048709Biological processoligodendrocyte differentiation
GO_0005886Cellular componentplasma membrane
GO_0004950Molecular functionchemokine receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0033612Molecular functionreceptor serine/threonine kinase binding

IV. Literature review

[source]
Gene nameGPR17
Protein nameUracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12)
G protein-coupled receptor 17 isoform b
G protein-coupled receptor 17
Synonyms
DescriptionFUNCTION: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. .

AccessionsENST00000272644.7 [Q13304-1]
ENST00000423019.1
ENST00000393018.3 [Q13304-1]
G4XH68
Q13304
ENST00000486700.2 [Q13304-2]
C9JWY5
ENST00000544369.5 [Q13304-1]