Insufficient scRNA-seq data for expression of PROKR2 at single-cell level.
Insufficient scRNA-seq data for expression of PROKR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 54% | 5.87 | 1438 / 2642 | 13% | 0.34 | 90 / 705 |
| heart | 59% | 2.66 | 509 / 861 | 0% | 0 | 0 / 0 |
| spleen | 53% | 2.44 | 127 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 43% | 2.56 | 401 / 929 | 0% | 0 | 0 / 0 |
| bladder | 38% | 0.81 | 8 / 21 | 2% | 0.22 | 9 / 504 |
| ovary | 18% | 0.49 | 32 / 180 | 13% | 0.40 | 57 / 430 |
| lung | 22% | 0.66 | 128 / 578 | 1% | 0.12 | 16 / 1155 |
| uterus | 18% | 0.44 | 31 / 170 | 4% | 0.29 | 19 / 459 |
| muscle | 22% | 0.68 | 177 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 18% | 0.47 | 239 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 16% | 0.44 | 59 / 359 | 1% | 0.22 | 4 / 286 |
| thymus | 15% | 0.57 | 95 / 653 | 3% | 0.07 | 17 / 605 |
| esophagus | 16% | 0.42 | 225 / 1445 | 1% | 0.02 | 2 / 183 |
| intestine | 16% | 0.44 | 157 / 966 | 0% | 0.01 | 1 / 527 |
| breast | 13% | 0.37 | 60 / 459 | 3% | 0.28 | 36 / 1118 |
| pancreas | 13% | 0.41 | 41 / 328 | 2% | 0.03 | 3 / 178 |
| prostate | 13% | 0.34 | 31 / 245 | 1% | 0.02 | 4 / 502 |
| skin | 10% | 0.35 | 181 / 1809 | 3% | 0.10 | 15 / 472 |
| adipose | 12% | 0.30 | 142 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 8% | 0.24 | 7 / 89 | 2% | 0.05 | 22 / 901 |
| adrenal gland | 6% | 0.15 | 15 / 258 | 1% | 0.31 | 3 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.21 | 2 / 29 |
| liver | 6% | 0.15 | 14 / 226 | 0% | 0.05 | 1 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.05 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007218 | Biological process | neuropeptide signaling pathway |
| GO_0007623 | Biological process | circadian rhythm |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004983 | Molecular function | neuropeptide Y receptor activity |
| Gene name | PROKR2 |
| Protein name | Prokineticin receptor 2 Prokineticin receptor 2 (PK-R2) (G-protein coupled receptor 73-like 1) (G-protein coupled receptor I5E) (GPR73b) (GPRg2) |
| Synonyms | PKR2 GPR73L1 |
| Description | FUNCTION: Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. |
| Accessions | ENST00000678254.1 ENST00000217270.4 ENST00000678059.1 A0A7I2V3D2 Q8NFJ6 |