LANCL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0031179Biological processpeptide modification
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_1990748Biological processcellular detoxification
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0043295Molecular functionglutathione binding
GO_0050750Molecular functionlow-density lipoprotein particle receptor binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0004364Molecular functionglutathione transferase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0017124Molecular functionSH3 domain binding

IV. Literature review

[source]
Gene nameLANCL1
Protein nameGlutathione S-transferase LANCL1 (EC 2.5.1.18) (40 kDa erythrocyte membrane protein) (p40) (LanC-like protein 1)
LanC like glutathione S-transferase 1
Glutathione S-transferase LANCL1 (EC 2.5.1.18) (LanC-like protein 1)
SynonymsGPR69A
hCG_16716
DescriptionFUNCTION: Functions as a glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (By similarity). May play a role in EPS8 signaling. Binds glutathione . .

AccessionsENST00000453956.1
ENST00000412863.1
ENST00000448951.6
H7C2E3
ENST00000233714.8
Q6FHH6
O43813
E9PHS0
ENST00000450366.7
ENST00000441020.7
ENST00000443314.5
F8WDS9
Q53TN2
ENST00000431941.6