Insufficient scRNA-seq data for expression of HCRTR1 at single-cell level.
Insufficient scRNA-seq data for expression of HCRTR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 99% | 88.59 | 648 / 653 | 2% | 0.02 | 11 / 605 |
breast | 93% | 35.53 | 426 / 459 | 1% | 0.02 | 14 / 1118 |
adipose | 91% | 32.92 | 1101 / 1204 | 0% | 0 | 0 / 0 |
muscle | 87% | 18.87 | 695 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 84% | 22.96 | 1115 / 1335 | 0% | 0 | 0 / 0 |
heart | 83% | 21.41 | 711 / 861 | 0% | 0 | 0 / 0 |
brain | 69% | 24.16 | 1835 / 2642 | 8% | 0.17 | 59 / 705 |
adrenal gland | 45% | 37.25 | 116 / 258 | 32% | 1.39 | 74 / 230 |
kidney | 64% | 15.55 | 57 / 89 | 1% | 0.01 | 5 / 901 |
esophagus | 64% | 25.89 | 924 / 1445 | 1% | 0.01 | 1 / 183 |
intestine | 63% | 8.29 | 604 / 966 | 1% | 0.02 | 4 / 527 |
uterus | 54% | 8.28 | 91 / 170 | 2% | 0.06 | 10 / 459 |
lung | 50% | 6.78 | 287 / 578 | 2% | 0.03 | 23 / 1155 |
prostate | 48% | 6.03 | 118 / 245 | 0% | 0.01 | 2 / 502 |
bladder | 43% | 3.62 | 9 / 21 | 3% | 0.04 | 13 / 504 |
stomach | 43% | 9.07 | 153 / 359 | 0% | 0.00 | 1 / 286 |
pancreas | 36% | 3.67 | 119 / 328 | 2% | 0.06 | 4 / 178 |
ovary | 35% | 3.66 | 63 / 180 | 1% | 0.01 | 3 / 430 |
skin | 29% | 2.88 | 519 / 1809 | 1% | 0.02 | 5 / 472 |
spleen | 22% | 2.04 | 54 / 241 | 0% | 0 | 0 / 0 |
liver | 9% | 0.88 | 21 / 226 | 0% | 0 | 0 / 406 |
peripheral blood | 9% | 0.72 | 79 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007631 | Biological process | feeding behavior |
GO_0051480 | Biological process | regulation of cytosolic calcium ion concentration |
GO_0007218 | Biological process | neuropeptide signaling pathway |
GO_0032870 | Biological process | cellular response to hormone stimulus |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0042277 | Molecular function | peptide binding |
GO_0017046 | Molecular function | peptide hormone binding |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0016499 | Molecular function | orexin receptor activity |
Gene name | HCRTR1 |
Protein name | Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Hypocretin receptor 1 |
Synonyms | |
Description | FUNCTION: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide . Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding . . |
Accessions | A0A8I5KTU6 ENST00000373706.9 ENST00000468521.1 ENST00000373705.1 O43613 ENST00000403528.7 A6NMV7 |