C5AR2 | OmnibusX

Name	Number of supported studies	Average coverage
macrophage	3 studies	20% ± 5%	Explore
non-classical monocyte	3 studies	30% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of C5AR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	93%	454.21	427 / 459	86%	12.06	961 / 1118
lung	99%	1128.25	575 / 578	63%	2.60	726 / 1155
kidney	82%	214.30	73 / 89	61%	2.21	550 / 901
thymus	66%	163.41	428 / 653	63%	1.43	380 / 605
adrenal gland	87%	239.87	224 / 258	33%	0.99	76 / 230
liver	58%	197.69	131 / 226	62%	2.99	251 / 406
bladder	90%	213.19	19 / 21	27%	0.74	137 / 504
spleen	100%	2625.24	241 / 241	0%	0	0 / 0
adipose	95%	713.98	1143 / 1204	0%	0	0 / 0
skin	78%	356.83	1415 / 1809	16%	0.25	77 / 472
intestine	73%	211.34	706 / 966	20%	0.40	107 / 527
peripheral blood	81%	4893.84	755 / 929	0%	0	0 / 0
blood vessel	77%	339.71	1027 / 1335	0%	0	0 / 0
esophagus	48%	121.70	699 / 1445	27%	0.66	50 / 183
brain	25%	51.55	664 / 2642	46%	0.99	327 / 705
stomach	48%	136.42	172 / 359	23%	0.36	65 / 286
uterus	42%	93.96	72 / 170	24%	1.27	109 / 459
pancreas	7%	13.64	24 / 328	55%	1.28	98 / 178
lymph node	0%	0	0 / 0	62%	1.83	18 / 29
heart	51%	177.75	436 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	47%	2.66	21 / 45
ovary	35%	86.50	63 / 180	10%	0.17	42 / 430
prostate	27%	51.53	66 / 245	1%	0.02	6 / 502
muscle	5%	8.06	42 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032677	Biological process	regulation of interleukin-8 production
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0006954	Biological process	inflammatory response
GO_0006935	Biological process	chemotaxis
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0032720	Biological process	negative regulation of tumor necrosis factor production
GO_0032715	Biological process	negative regulation of interleukin-6 production
GO_0090024	Biological process	negative regulation of neutrophil chemotaxis
GO_0038178	Biological process	complement component C5a signaling pathway
GO_0002430	Biological process	complement receptor mediated signaling pathway
GO_0045177	Cellular component	apical part of cell
GO_0005886	Cellular component	plasma membrane
GO_0009925	Cellular component	basal plasma membrane
GO_0004878	Molecular function	complement component C5a receptor activity
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0005515	Molecular function	protein binding

Gene name	C5AR2
Protein name	C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Synonyms	C5L2 GPR77
Description	FUNCTION: Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. .
Accessions	Q9P296 ENST00000600626.1 ENST00000595464.3

C5AR2 report