OXER1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OXER1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OXER1 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0050648Molecular function5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding
GO_0050647Molecular function5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
GO_0050646Molecular function5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding

IV. Literature review

[source]
Gene nameOXER1
Protein nameAlternative protein OXER1
Oxoeicosanoid receptor 1 (5-oxo-ETE G-protein coupled receptor) (G-protein coupled receptor 170) (G-protein coupled receptor R527) (G-protein coupled receptor TG1019)
SynonymsTG1019
GPR170
DescriptionFUNCTION: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. .

AccessionsQ8TDS5
ENST00000378661.4
L8E891