FPR1 | OmnibusX

Name	Number of supported studies	Average coverage
macrophage	30 studies	26% ± 10%	Explore
classical monocyte	27 studies	51% ± 16%	Explore
non-classical monocyte	23 studies	38% ± 12%	Explore
monocyte	21 studies	38% ± 13%	Explore
neutrophil	15 studies	62% ± 20%	Explore
conventional dendritic cell	14 studies	25% ± 9%	Explore
myeloid cell	10 studies	29% ± 13%	Explore
dendritic cell	9 studies	31% ± 14%	Explore
alveolar macrophage	6 studies	27% ± 12%	Explore
intermediate monocyte	4 studies	68% ± 13%	Explore
microglial cell	3 studies	42% ± 14%	Explore

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	4229.25	576 / 578	88%	16.23	1012 / 1155
breast	61%	414.18	278 / 459	80%	8.43	897 / 1118
brain	34%	279.05	899 / 2642	93%	41.73	657 / 705
kidney	47%	305.67	42 / 89	79%	13.91	710 / 901
adrenal gland	77%	532.61	199 / 258	40%	3.88	91 / 230
bladder	48%	515.86	10 / 21	62%	8.96	314 / 504
pancreas	19%	97.38	61 / 328	88%	18.74	157 / 178
stomach	36%	345.76	131 / 359	70%	9.95	200 / 286
intestine	43%	301.07	418 / 966	62%	9.60	329 / 527
spleen	100%	10511.70	241 / 241	0%	0	0 / 0
thymus	38%	185.55	248 / 653	62%	5.18	374 / 605
uterus	35%	220.66	60 / 170	64%	6.30	296 / 459
lymph node	0%	0	0 / 0	97%	59.99	28 / 29
ovary	28%	134.21	51 / 180	66%	7.22	285 / 430
esophagus	33%	216.21	484 / 1445	58%	4.49	106 / 183
skin	23%	109.73	419 / 1809	66%	8.10	312 / 472
adipose	82%	1307.56	990 / 1204	0%	0	0 / 0
peripheral blood	81%	95524.39	755 / 929	0%	0	0 / 0
liver	49%	308.10	111 / 226	31%	2.68	126 / 406
prostate	38%	215.60	92 / 245	39%	2.55	194 / 502
blood vessel	71%	702.12	943 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	64%	6.80	29 / 45
heart	50%	322.18	428 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.28	5 / 80
muscle	6%	19.95	46 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007188	Biological process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0006954	Biological process	inflammatory response
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0007165	Biological process	signal transduction
GO_0006935	Biological process	chemotaxis
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0007263	Biological process	nitric oxide mediated signal transduction
GO_0002430	Biological process	complement receptor mediated signaling pathway
GO_0030667	Cellular component	secretory granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0035577	Cellular component	azurophil granule membrane
GO_0101003	Cellular component	ficolin-1-rich granule membrane
GO_0005737	Cellular component	cytoplasm
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0004982	Molecular function	N-formyl peptide receptor activity
GO_0004875	Molecular function	complement receptor activity
GO_0001664	Molecular function	G protein-coupled receptor binding
GO_0005124	Molecular function	scavenger receptor binding
GO_0050786	Molecular function	RAGE receptor binding
GO_0005515	Molecular function	protein binding

Gene name	FPR1
Protein name	fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor) (FPR) (N-formylpeptide chemoattractant receptor) fMet-Leu-Phe receptor
Synonyms
Description	FUNCTION: High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors . Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release . This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system . Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release . Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis . .
Accessions	ENST00000594900.1 ENST00000600815.1 ENST00000594900.2 ENST00000304748.5 P21462 M0QZT0 ENST00000595042.5 ENST00000600815.2 M0R315

FPR1 report