OR51E2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of OR51E2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	98%	3693.76	239 / 245	100%	714.19	501 / 502
intestine	92%	907.38	892 / 966	29%	0.86	151 / 527
uterus	92%	161.40	156 / 170	12%	0.52	53 / 459
bladder	76%	57.67	16 / 21	17%	0.60	84 / 504
kidney	39%	26.83	35 / 89	51%	2.28	462 / 901
breast	69%	64.28	318 / 459	14%	0.26	159 / 1118
adipose	67%	61.18	807 / 1204	0%	0	0 / 0
blood vessel	64%	661.89	861 / 1335	0%	0	0 / 0
ovary	56%	70.51	100 / 180	1%	0.02	3 / 430
stomach	38%	48.78	135 / 359	17%	0.35	48 / 286
esophagus	38%	29.71	547 / 1445	4%	0.15	8 / 183
muscle	38%	21.56	308 / 803	0%	0	0 / 0
thymus	22%	13.62	145 / 653	3%	0.07	21 / 605
skin	18%	9.48	331 / 1809	2%	0.05	8 / 472
heart	15%	6.46	128 / 861	0%	0	0 / 0
brain	9%	4.77	226 / 2642	3%	0.08	24 / 705
pancreas	1%	0.33	3 / 328	9%	0.17	16 / 178
adrenal gland	0%	0	0 / 258	7%	0.13	15 / 230
peripheral blood	4%	2.12	35 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.07	3 / 80
lymph node	0%	0	0 / 0	3%	0.05	1 / 29
lung	0%	0.05	1 / 578	3%	0.21	37 / 1155
tonsil	0%	0	0 / 0	2%	0.02	1 / 45
spleen	2%	0.63	4 / 241	0%	0	0 / 0
liver	0%	0	0 / 226	1%	0.03	6 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071398	Biological process	cellular response to fatty acid
GO_0050911	Biological process	detection of chemical stimulus involved in sensory perception of smell
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0030318	Biological process	melanocyte differentiation
GO_0097325	Biological process	melanocyte proliferation
GO_1900135	Biological process	positive regulation of renin secretion into blood stream
GO_0045777	Biological process	positive regulation of blood pressure
GO_0016477	Biological process	cell migration
GO_0043401	Biological process	steroid hormone receptor signaling pathway
GO_0043229	Cellular component	intracellular organelle
GO_0031901	Cellular component	early endosome membrane
GO_0005886	Cellular component	plasma membrane
GO_0038023	Molecular function	signaling receptor activity
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0004984	Molecular function	olfactory receptor activity
GO_0003707	Molecular function	nuclear steroid receptor activity

Gene name	OR51E2
Protein name	Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor) Olfactory receptor family 51 subfamily E member 2 Olfactory receptor
Synonyms	PSGR
Description	FUNCTION: Olfactory receptor . Activated by the odorant, beta-ionone, a synthetic terpenoid . The activity of this receptor is probably mediated by G-proteins leading to the elevation of intracellular Ca(2+), cAMP and activation of the protein kinases PKA and MAPK3/MAPK1 . Stimulation of OR51E2 by beta-ionone affects melanocyte proliferation, differentiation, and melanogenesis . Activation of OR51E2 by beta-ionone increases proliferation and migration of primary retinal pigment epithelial (RPE) cells . Activated also by the short-chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure . May also be activated by steroid hormones and regulate cell proliferation . Activated by L-lactate in glomus cells (By similarity). .
Accessions	ENST00000396950.4 E9PPJ8 A0A126GVK0 Q9H255 ENST00000641638.1 ENST00000532598.1

OR51E2 report