GRM8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0007196Biological processadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0007216Biological processG protein-coupled glutamate receptor signaling pathway
GO_0051966Biological processregulation of synaptic transmission, glutamatergic
GO_0005886Cellular componentplasma membrane
GO_0008066Molecular functionglutamate receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0001642Molecular functiongroup III metabotropic glutamate receptor activity

IV. Literature review

[source]
Gene nameGRM8
Protein nameMetabotropic glutamate receptor 8 (mGluR8)
Glutamate metabotropic receptor 8
SynonymsGPRC1H
MGLUR8
DescriptionFUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. .

AccessionsENST00000341617.7 [O00222-3]
ENST00000457830.1
E7ETK3
C9J7I1
ENST00000706915.1
ENST00000472701.5 [O00222-2]
ENST00000706917.1 [O00222-1]
A0A9L9PYG5
ENST00000465844.1
ENST00000339582.7 [O00222-1]
H7C4V5
ENST00000412160.1
ENST00000358373.8 [O00222-2]
ENST00000706916.1 [O00222-2]
O00222