Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 9 studies | 42% ± 18% | |
GABAergic neuron | 7 studies | 34% ± 18% | |
interneuron | 6 studies | 38% ± 20% | |
endothelial cell | 5 studies | 34% ± 11% | |
neuron | 4 studies | 23% ± 10% | |
oligodendrocyte precursor cell | 4 studies | 21% ± 3% | |
amacrine cell | 4 studies | 52% ± 19% | |
pericyte | 3 studies | 55% ± 14% | |
GABAergic interneuron | 3 studies | 27% ± 2% | |
GABAergic amacrine cell | 3 studies | 70% ± 8% | |
glycinergic amacrine cell | 3 studies | 41% ± 7% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 9 studies | 31% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 231.51 | 2589 / 2642 | 68% | 1.80 | 477 / 705 |
kidney | 71% | 55.84 | 63 / 89 | 70% | 4.03 | 628 / 901 |
liver | 84% | 116.48 | 190 / 226 | 14% | 0.66 | 58 / 406 |
intestine | 30% | 23.86 | 292 / 966 | 57% | 5.48 | 302 / 527 |
bladder | 62% | 93.62 | 13 / 21 | 21% | 1.91 | 105 / 504 |
stomach | 30% | 11.40 | 108 / 359 | 42% | 4.92 | 121 / 286 |
thymus | 68% | 45.97 | 441 / 653 | 4% | 0.07 | 26 / 605 |
ovary | 61% | 137.64 | 110 / 180 | 4% | 0.12 | 19 / 430 |
adrenal gland | 15% | 10.70 | 38 / 258 | 49% | 2.60 | 113 / 230 |
lung | 49% | 38.88 | 286 / 578 | 4% | 0.18 | 49 / 1155 |
heart | 41% | 46.90 | 357 / 861 | 0% | 0 | 0 / 0 |
pancreas | 19% | 8.73 | 62 / 328 | 9% | 0.19 | 16 / 178 |
prostate | 16% | 6.50 | 39 / 245 | 4% | 0.10 | 20 / 502 |
uterus | 1% | 0.53 | 2 / 170 | 16% | 0.79 | 75 / 459 |
peripheral blood | 17% | 20.82 | 159 / 929 | 0% | 0 | 0 / 0 |
esophagus | 6% | 3.60 | 87 / 1445 | 10% | 0.18 | 18 / 183 |
breast | 1% | 0.61 | 5 / 459 | 9% | 0.16 | 104 / 1118 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.12 | 4 / 45 |
eye | 0% | 0 | 0 / 0 | 5% | 0.07 | 4 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
blood vessel | 3% | 1.44 | 41 / 1335 | 0% | 0 | 0 / 0 |
skin | 0% | 0.11 | 7 / 1809 | 2% | 0.06 | 11 / 472 |
spleen | 1% | 0.56 | 2 / 241 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.14 | 4 / 803 | 0% | 0 | 0 / 0 |
adipose | 0% | 0.02 | 1 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0007196 | Biological process | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway |
GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
GO_0007216 | Biological process | G protein-coupled glutamate receptor signaling pathway |
GO_0051966 | Biological process | regulation of synaptic transmission, glutamatergic |
GO_0005886 | Cellular component | plasma membrane |
GO_0008066 | Molecular function | glutamate receptor activity |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0001642 | Molecular function | group III metabotropic glutamate receptor activity |
Gene name | GRM8 |
Protein name | Metabotropic glutamate receptor 8 (mGluR8) Glutamate metabotropic receptor 8 |
Synonyms | GPRC1H MGLUR8 |
Description | FUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. . |
Accessions | ENST00000341617.7 [O00222-3] ENST00000457830.1 E7ETK3 C9J7I1 ENST00000706915.1 ENST00000472701.5 [O00222-2] ENST00000706917.1 [O00222-1] A0A9L9PYG5 ENST00000465844.1 ENST00000339582.7 [O00222-1] H7C4V5 ENST00000412160.1 ENST00000358373.8 [O00222-2] ENST00000706916.1 [O00222-2] O00222 |