Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 83% ± 11% | |
| amacrine cell | 5 studies | 40% ± 11% | |
| retinal ganglion cell | 4 studies | 41% ± 31% | |
| retinal bipolar neuron | 3 studies | 51% ± 2% | |
| retinal cone cell | 3 studies | 52% ± 10% | |
| retina horizontal cell | 3 studies | 32% ± 9% | |
| microglial cell | 3 studies | 49% ± 9% | |
| Mueller cell | 3 studies | 44% ± 16% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 7 studies | 54% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 88% | 9.15 | 159 / 180 | 1% | 0.02 | 5 / 430 |
| brain | 80% | 19.89 | 2115 / 2642 | 3% | 0.05 | 18 / 705 |
| uterus | 79% | 5.97 | 135 / 170 | 0% | 0 | 0 / 459 |
| prostate | 71% | 4.37 | 173 / 245 | 0% | 0 | 0 / 502 |
| blood vessel | 67% | 3.48 | 900 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 65% | 3.08 | 156 / 241 | 0% | 0 | 0 / 0 |
| breast | 63% | 3.33 | 291 / 459 | 0% | 0.01 | 5 / 1118 |
| lung | 63% | 3.27 | 364 / 578 | 0% | 0.00 | 2 / 1155 |
| bladder | 62% | 3.14 | 13 / 21 | 0% | 0 | 0 / 504 |
| thymus | 62% | 3.53 | 402 / 653 | 0% | 0.00 | 1 / 605 |
| adipose | 61% | 2.90 | 735 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 58% | 3.34 | 52 / 89 | 0% | 0.00 | 2 / 901 |
| intestine | 56% | 2.50 | 540 / 966 | 0% | 0.01 | 2 / 527 |
| skin | 49% | 12.09 | 881 / 1809 | 0% | 0 | 0 / 472 |
| esophagus | 45% | 1.89 | 657 / 1445 | 1% | 0.01 | 1 / 183 |
| stomach | 40% | 1.63 | 143 / 359 | 0% | 0 | 0 / 286 |
| pancreas | 39% | 1.39 | 129 / 328 | 0% | 0 | 0 / 178 |
| adrenal gland | 37% | 1.38 | 96 / 258 | 0% | 0 | 0 / 230 |
| liver | 34% | 1.07 | 76 / 226 | 0% | 0.01 | 2 / 406 |
| heart | 34% | 1.18 | 289 / 861 | 0% | 0 | 0 / 0 |
| muscle | 24% | 0.75 | 196 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 22% | 0.68 | 205 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 19% | 68.49 | 15 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007601 | Biological process | visual perception |
| GO_0016056 | Biological process | G protein-coupled opsin signaling pathway |
| GO_0007602 | Biological process | phototransduction |
| GO_0071482 | Biological process | cellular response to light stimulus |
| GO_0045494 | Biological process | photoreceptor cell maintenance |
| GO_1904389 | Biological process | rod bipolar cell differentiation |
| GO_0071800 | Biological process | podosome assembly |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007603 | Biological process | phototransduction, visible light |
| GO_0009642 | Biological process | response to light intensity |
| GO_0050960 | Biological process | detection of temperature stimulus involved in thermoception |
| GO_0000226 | Biological process | microtubule cytoskeleton organization |
| GO_0010467 | Biological process | gene expression |
| GO_0043052 | Biological process | thermotaxis |
| GO_0016038 | Biological process | absorption of visible light |
| GO_1990913 | Cellular component | sperm head plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0001750 | Cellular component | photoreceptor outer segment |
| GO_0016020 | Cellular component | membrane |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0060170 | Cellular component | ciliary membrane |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0042622 | Cellular component | photoreceptor outer segment membrane |
| GO_0097381 | Cellular component | photoreceptor disc membrane |
| GO_0060342 | Cellular component | photoreceptor inner segment membrane |
| GO_0030660 | Cellular component | Golgi-associated vesicle membrane |
| GO_0097225 | Cellular component | sperm midpiece |
| GO_0120200 | Cellular component | rod photoreceptor outer segment |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0008020 | Molecular function | G protein-coupled photoreceptor activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005502 | Molecular function | 11-cis retinal binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | RHO |
| Protein name | Rhodopsin (Opsin-2) Rhodopsin |
| Synonyms | OPN2 |
| Description | FUNCTION: Photoreceptor required for image-forming vision at low light intensity . Required for photoreceptor cell viability after birth . Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins . Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling . . |
| Accessions | A0A076V826 A0A0K0Q0G7 ENST00000296271.4 A0A0M3R835 P08100 |
