GRM6 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of GRM6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	68.59	2601 / 2642	11%	0.16	77 / 705
ovary	98%	46.03	177 / 180	9%	0.13	38 / 430
bladder	100%	42.52	21 / 21	3%	0.10	14 / 504
kidney	100%	48.40	89 / 89	1%	0.02	11 / 901
thymus	100%	60.31	652 / 653	1%	0.01	6 / 605
uterus	99%	61.31	169 / 170	1%	0.06	3 / 459
prostate	100%	116.68	244 / 245	0%	0.00	1 / 502
spleen	98%	35.94	235 / 241	0%	0	0 / 0
pancreas	96%	31.87	314 / 328	2%	0.05	3 / 178
breast	94%	30.18	431 / 459	2%	0.03	20 / 1118
lung	94%	34.31	545 / 578	1%	0.03	16 / 1155
intestine	92%	41.93	893 / 966	0%	0.00	1 / 527
heart	90%	26.80	778 / 861	0%	0	0 / 0
esophagus	86%	35.06	1239 / 1445	2%	0.03	3 / 183
stomach	87%	26.46	313 / 359	0%	0	0 / 286
blood vessel	86%	24.36	1154 / 1335	0%	0	0 / 0
adipose	85%	25.38	1027 / 1204	0%	0	0 / 0
adrenal gland	74%	19.09	190 / 258	6%	0.08	13 / 230
skin	62%	14.11	1123 / 1809	0%	0.00	1 / 472
liver	58%	22.77	130 / 226	0%	0.03	1 / 406
muscle	7%	0.93	54 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.61	5 / 80
peripheral blood	0%	0.01	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007196	Biological process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO_0060041	Biological process	retina development in camera-type eye
GO_0007216	Biological process	G protein-coupled glutamate receptor signaling pathway
GO_0051966	Biological process	regulation of synaptic transmission, glutamatergic
GO_0050908	Biological process	detection of light stimulus involved in visual perception
GO_0009584	Biological process	detection of visible light
GO_0007268	Biological process	chemical synaptic transmission
GO_1905665	Biological process	positive regulation of calcium ion import across plasma membrane
GO_0007626	Biological process	locomotory behavior
GO_0035841	Cellular component	new growing cell tip
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030425	Cellular component	dendrite
GO_0000139	Cellular component	Golgi membrane
GO_0045202	Cellular component	synapse
GO_0042803	Molecular function	protein homodimerization activity
GO_0008066	Molecular function	glutamate receptor activity
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0001640	Molecular function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO_0005515	Molecular function	protein binding

Gene name	GRM6
Protein name	Metabotropic glutamate receptor 6 (mGluR6)
Synonyms	GPRC1F MGLUR6
Description	FUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision. .
Accessions	ENST00000231188.9 ENST00000650031.1 O15303 ENST00000517717.3

GRM6 report