TAS2R8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAS2R8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAS2R8 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0001580Biological processdetection of chemical stimulus involved in sensory perception of bitter taste
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding
GO_0008527Molecular functiontaste receptor activity
GO_0033038Molecular functionbitter taste receptor activity

IV. Literature review

[source]
Gene nameTAS2R8
Protein nameTaste receptor type 2
Taste receptor type 2 member 8 (T2R8) (Taste receptor family B member 5) (TRB5)
Synonyms
DescriptionFUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. .

AccessionsENST00000572823.1
Q4KN04
ENST00000610444.2
Q9NYW2
ENST00000240615.3