GPR83 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GPR83 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPR83 at tissue level.

III. Associated gene sets

GO_0007631Biological processfeeding behavior
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0051384Biological processresponse to glucocorticoid
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0097730Cellular componentnon-motile cilium
GO_0005929Cellular componentcilium
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0008188Molecular functionneuropeptide receptor activity
GO_0004983Molecular functionneuropeptide Y receptor activity

IV. Literature review

[source]
Gene nameGPR83
Protein nameG-protein coupled receptor 83 (G-protein coupled receptor 72)
G protein-coupled receptor 83
SynonymsJP05
GPR72
KIAA1540
DescriptionFUNCTION: G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN . Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors (By similarity). .

AccessionsQ6NWR3
ENST00000539203.2 [Q9NYM4-2]
Q9NYM4
ENST00000243673.7 [Q9NYM4-1]