Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasma cell | 22 studies | 51% ± 19% | |
| plasmablast | 10 studies | 59% ± 25% | |
| IgA plasma cell | 7 studies | 51% ± 13% | |
| IgG plasma cell | 7 studies | 32% ± 14% | |
| IgM plasma cell | 4 studies | 41% ± 8% | |
| B cell | 3 studies | 23% ± 10% |
Insufficient scRNA-seq data for expression of TNFRSF17 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 57% | 37.42 | 332 / 578 | 78% | 10.03 | 896 / 1155 |
| stomach | 64% | 74.05 | 230 / 359 | 57% | 4.60 | 164 / 286 |
| intestine | 55% | 223.88 | 530 / 966 | 54% | 5.03 | 284 / 527 |
| spleen | 100% | 790.35 | 241 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 167.37 | 28 / 29 |
| breast | 36% | 33.76 | 165 / 459 | 52% | 5.18 | 586 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 80% | 12.61 | 36 / 45 |
| bladder | 33% | 23.00 | 7 / 21 | 44% | 6.89 | 220 / 504 |
| peripheral blood | 74% | 882.48 | 684 / 929 | 0% | 0 | 0 / 0 |
| thymus | 26% | 30.57 | 171 / 653 | 33% | 6.45 | 202 / 605 |
| uterus | 21% | 5.24 | 36 / 170 | 37% | 3.25 | 171 / 459 |
| esophagus | 17% | 8.13 | 241 / 1445 | 40% | 3.04 | 73 / 183 |
| pancreas | 6% | 1.30 | 19 / 328 | 46% | 3.70 | 81 / 178 |
| skin | 3% | 0.50 | 49 / 1809 | 41% | 5.73 | 194 / 472 |
| kidney | 22% | 15.78 | 20 / 89 | 19% | 1.55 | 170 / 901 |
| ovary | 12% | 2.24 | 22 / 180 | 22% | 1.28 | 95 / 430 |
| liver | 20% | 4.82 | 46 / 226 | 11% | 0.88 | 44 / 406 |
| prostate | 20% | 7.33 | 48 / 245 | 10% | 0.60 | 51 / 502 |
| adrenal gland | 8% | 1.82 | 21 / 258 | 3% | 0.14 | 8 / 230 |
| adipose | 11% | 4.22 | 135 / 1204 | 0% | 0 | 0 / 0 |
| brain | 8% | 2.25 | 224 / 2642 | 2% | 0.10 | 11 / 705 |
| blood vessel | 8% | 3.69 | 101 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.84 | 3 / 80 |
| heart | 2% | 0.51 | 17 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.18 | 8 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0002260 | Biological process | lymphocyte homeostasis |
| GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TNFRSF17 |
| Protein name | Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269) TNF receptor superfamily member 17 Tumor necrosis factor receptor superfamily, member 17 |
| Synonyms | BCMA BCM |
| Description | FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. . |
| Accessions | Q6PE46 ENST00000562385.1 ENST00000396495.3 [Q02223-2] ENST00000053243.6 [Q02223-1] Q02223 H3BMB5 |
