CLEC4C | OmnibusX

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	20 studies	63% ± 18%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC4C at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
peripheral blood	77%	54.52	717 / 929	0%	0	0 / 0
spleen	62%	8.41	150 / 241	0%	0	0 / 0
lung	26%	2.25	148 / 578	9%	0.16	104 / 1155
lymph node	0%	0	0 / 0	24%	0.90	7 / 29
breast	6%	0.35	28 / 459	12%	0.32	132 / 1118
tonsil	0%	0	0 / 0	13%	0.21	6 / 45
skin	4%	0.27	78 / 1809	7%	0.21	35 / 472
ovary	9%	1.24	17 / 180	1%	0.01	3 / 430
thymus	4%	0.32	29 / 653	5%	0.13	32 / 605
adipose	7%	0.43	84 / 1204	0%	0	0 / 0
stomach	3%	0.13	10 / 359	4%	0.06	11 / 286
esophagus	2%	0.10	28 / 1445	4%	0.07	7 / 183
intestine	3%	0.22	33 / 966	1%	0.03	6 / 527
liver	3%	0.14	7 / 226	0%	0.00	1 / 406
kidney	2%	0.18	2 / 89	1%	0.04	9 / 901
uterus	1%	0.06	2 / 170	2%	0.03	8 / 459
heart	3%	0.14	22 / 861	0%	0	0 / 0
pancreas	0%	0.02	1 / 328	2%	0.04	4 / 178
blood vessel	3%	0.16	34 / 1335	0%	0	0 / 0
prostate	1%	0.09	3 / 245	1%	0.02	5 / 502
adrenal gland	0%	0.02	1 / 258	2%	0.03	4 / 230
bladder	0%	0	0 / 21	2%	0.04	9 / 504
brain	1%	0.08	33 / 2642	0%	0.01	1 / 705
muscle	1%	0.08	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002250	Biological process	adaptive immune response
GO_0061760	Biological process	antifungal innate immune response
GO_0030667	Cellular component	secretory granule membrane
GO_0009897	Cellular component	external side of plasma membrane
GO_0070821	Cellular component	tertiary granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0101003	Cellular component	ficolin-1-rich granule membrane
GO_0030246	Molecular function	carbohydrate binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	CLEC4C
Protein name	C-type lectin domain family 4 member C (Blood dendritic cell antigen 2) (BDCA-2) (C-type lectin superfamily member 7) (Dendritic lectin) (CD antigen CD303) C-type lectin domain family 4 member C
Synonyms	HECL DLEC UNQ9361/PRO34150 CLECSF11 CLECSF7 BDCA2
Description	FUNCTION: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells . Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man . Binds to serum IgG . Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells . May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells . May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium . .
Accessions	H0YGB2 ENST00000540085.5 [Q8WTT0-2] ENST00000360345.8 [Q8WTT0-1] ENST00000354629.9 [Q8WTT0-2] ENST00000542353.5 [Q8WTT0-1] ENST00000537530.1 H0YFH6 ENST00000543765.1 Q8WTT0

CLEC4C report