Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 2780.61 | 652 / 653 | 95% | 95.43 | 575 / 605 |
| breast | 100% | 4108.07 | 459 / 459 | 95% | 84.11 | 1059 / 1118 |
| kidney | 100% | 3027.21 | 89 / 89 | 95% | 123.83 | 852 / 901 |
| lung | 100% | 7278.52 | 578 / 578 | 94% | 128.97 | 1083 / 1155 |
| uterus | 97% | 1831.82 | 165 / 170 | 87% | 109.37 | 401 / 459 |
| prostate | 97% | 1912.10 | 237 / 245 | 86% | 45.20 | 431 / 502 |
| intestine | 94% | 2354.40 | 912 / 966 | 82% | 75.18 | 432 / 527 |
| stomach | 87% | 1673.70 | 312 / 359 | 85% | 88.53 | 243 / 286 |
| bladder | 86% | 1463.62 | 18 / 21 | 85% | 79.79 | 427 / 504 |
| skin | 74% | 1197.95 | 1338 / 1809 | 86% | 112.63 | 406 / 472 |
| esophagus | 86% | 1181.14 | 1249 / 1445 | 73% | 52.33 | 133 / 183 |
| adrenal gland | 100% | 3972.12 | 257 / 258 | 57% | 26.81 | 130 / 230 |
| pancreas | 55% | 648.48 | 179 / 328 | 94% | 107.54 | 168 / 178 |
| ovary | 54% | 598.10 | 97 / 180 | 93% | 126.88 | 402 / 430 |
| liver | 46% | 484.77 | 105 / 226 | 71% | 61.22 | 288 / 406 |
| brain | 36% | 478.53 | 942 / 2642 | 73% | 62.32 | 516 / 705 |
| adipose | 100% | 4737.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 665.59 | 29 / 29 |
| spleen | 100% | 9194.68 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 4884.79 | 900 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 101.43 | 41 / 45 |
| blood vessel | 88% | 1889.63 | 1173 / 1335 | 0% | 0 | 0 / 0 |
| heart | 73% | 821.98 | 630 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 64% | 37.64 | 51 / 80 |
| muscle | 33% | 293.65 | 263 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019886 | Biological process | antigen processing and presentation of exogenous peptide antigen via MHC class II |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0050870 | Biological process | positive regulation of T cell activation |
| GO_0050778 | Biological process | positive regulation of immune response |
| GO_0002503 | Biological process | peptide antigen assembly with MHC class II protein complex |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0009986 | Cellular component | cell surface |
| GO_0031902 | Cellular component | late endosome membrane |
| GO_0042613 | Cellular component | MHC class II protein complex |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0023026 | Molecular function | MHC class II protein complex binding |
| GO_0042605 | Molecular function | peptide antigen binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HLA-DMA |
| Protein name | HLA class II histocompatibility antigen, DM alpha chain (MHC class II antigen DMA) (Really interesting new gene 6 protein) HLA-DMA HLA class II histocompatibility antigen, DM alpha chain (Major histocompatibility complex, class II, DM alpha) HLA class II histocompatibility antigen, DM alpha chain MHC class II antigen HLA-DMA protein Major histocompatibility complex, class II, DM alpha DMA protein (MHC class II antigen) (Major histocompatibility complex, class II, DM alpha) (cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha (HLA-DMA), mRNA) |
| Synonyms | DMA RING6 hCG_2001572 |
| Description | FUNCTION: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. . |
| Accessions | ENST00000426176.1 ENST00000443447.6 ENST00000395305.7 ENST00000451753.6 A0A140T9N4 A0A140T9N2 ENST00000395303.7 A0A1V0E3J7 ENST00000451148.6 A0A1V0E3J1 A2AAT8 A0A1V0E3M5 ENST00000422196.1 O77837 ENST00000422832.1 A0A1V0E3M0 ENST00000416806.1 A0A1V0E3L4 ENST00000437285.1 ENST00000456486.1 A0A1V0E3K1 ENST00000434337.6 ENST00000383230.8 A0A1V0E3I5 Q5SP00 F6S093 A0A140T9N9 ENST00000456800.1 A0A1V0E3J5 ENST00000452615.6 ENST00000454298.1 A0A140T9N7 ENST00000419041.6 ENST00000453490.6 ENST00000452330.6 A0A140T9E7 A0A140T9C7 A0A1V0E3M2 ENST00000439054.6 A0A140T9D1 ENST00000457285.6 ENST00000418042.1 A0A140T985 A0A1V0E3I4 Q6ICR9 ENST00000441375.6 ENST00000440717.1 ENST00000416297.1 ENST00000441171.1 A0A1V0E3L1 A0A140T9H8 A0A1V0E3L2 ENST00000420299.6 A0A140T9X4 ENST00000433630.1 ENST00000374843.9 A0A140T9G2 ENST00000383227.8 A0A140T995 A0A140T9V7 Q31604 A0A140T9T3 ENST00000419231.1 ENST00000420931.6 ENST00000452434.6 H0Y732 ENST00000432991.6 A0A140T9C4 ENST00000450601.6 ENST00000435503.6 ENST00000383228.8 Q29878 ENST00000412394.1 ENST00000458066.1 P28067 ENST00000452703.6 A0A140T9K8 X5D2V7 A0A1V0E3L9 A0A140T9T2 |
