Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 19 studies | 24% ± 9% | |
| B cell | 13 studies | 23% ± 7% | |
| CD16-positive, CD56-dim natural killer cell, human | 10 studies | 26% ± 11% | |
| CD16-negative, CD56-bright natural killer cell, human | 9 studies | 25% ± 9% | |
| naive B cell | 7 studies | 21% ± 5% | |
| memory B cell | 6 studies | 20% ± 2% | |
| CD8-positive, alpha-beta T cell | 5 studies | 28% ± 10% | |
| classical monocyte | 5 studies | 27% ± 12% | |
| gamma-delta T cell | 5 studies | 20% ± 5% | |
| conventional dendritic cell | 4 studies | 26% ± 16% | |
| endothelial cell | 4 studies | 24% ± 10% | |
| myeloid cell | 4 studies | 23% ± 6% | |
| epithelial cell | 4 studies | 23% ± 9% | |
| macrophage | 4 studies | 23% ± 7% | |
| CD8-positive, alpha-beta memory T cell | 4 studies | 19% ± 4% | |
| microglial cell | 4 studies | 18% ± 1% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 32% ± 12% | |
| mature NK T cell | 3 studies | 27% ± 13% | |
| immature B cell | 3 studies | 25% ± 7% | |
| T cell | 3 studies | 19% ± 3% | |
| innate lymphoid cell | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 5 studies | 27% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3289.22 | 1445 / 1445 | 100% | 33.84 | 183 / 183 |
| ovary | 100% | 2328.43 | 180 / 180 | 100% | 41.24 | 430 / 430 |
| uterus | 100% | 3641.79 | 170 / 170 | 100% | 39.42 | 459 / 459 |
| thymus | 100% | 3008.06 | 652 / 653 | 100% | 38.79 | 602 / 605 |
| lung | 100% | 6892.66 | 578 / 578 | 99% | 39.42 | 1146 / 1155 |
| stomach | 100% | 2479.30 | 359 / 359 | 99% | 33.31 | 283 / 286 |
| intestine | 100% | 4406.37 | 966 / 966 | 99% | 28.58 | 520 / 527 |
| liver | 99% | 1776.96 | 223 / 226 | 100% | 28.09 | 405 / 406 |
| bladder | 100% | 3427.38 | 21 / 21 | 98% | 37.13 | 495 / 504 |
| prostate | 100% | 3533.78 | 244 / 245 | 99% | 28.90 | 495 / 502 |
| breast | 100% | 3128.07 | 459 / 459 | 98% | 32.03 | 1097 / 1118 |
| skin | 98% | 1703.83 | 1775 / 1809 | 100% | 57.04 | 471 / 472 |
| kidney | 100% | 3055.25 | 89 / 89 | 97% | 35.33 | 875 / 901 |
| adrenal gland | 100% | 3237.16 | 258 / 258 | 92% | 21.88 | 212 / 230 |
| brain | 73% | 1032.20 | 1936 / 2642 | 100% | 33.91 | 703 / 705 |
| pancreas | 68% | 835.18 | 222 / 328 | 99% | 42.18 | 176 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 53.86 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 128.14 | 29 / 29 |
| peripheral blood | 100% | 17818.17 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 17740.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 40.02 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 61.20 | 1 / 1 |
| adipose | 100% | 3448.77 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 2802.75 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 2182.40 | 852 / 861 | 0% | 0 | 0 / 0 |
| muscle | 45% | 452.75 | 365 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045786 | Biological process | negative regulation of cell cycle |
| GO_0090162 | Biological process | establishment of epithelial cell polarity |
| GO_0007165 | Biological process | signal transduction |
| GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
| GO_0003382 | Biological process | epithelial cell morphogenesis |
| GO_0007162 | Biological process | negative regulation of cell adhesion |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0042631 | Biological process | cellular response to water deprivation |
| GO_0030308 | Biological process | negative regulation of cell growth |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005096 | Molecular function | GTPase activator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SIPA1 |
| Protein name | Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1) Signal-induced proliferation-associated 1 |
| Synonyms | SPA1 |
| Description | FUNCTION: GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state . Affects cell cycle progression (By similarity). . |
| Accessions | ENST00000527525.5 E9PIB3 ENST00000394224.3 ENST00000534313.6 Q96FS4 F6RY50 ENST00000533361.1 |