Insufficient scRNA-seq data for expression of LILRA3 at single-cell level.
Insufficient scRNA-seq data for expression of LILRA3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adipose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
brain | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
breast | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
esophagus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
intestine | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
kidney | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lung | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
pancreas | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
prostate | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
skin | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
stomach | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
thymus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
uterus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0002250 | Biological process | adaptive immune response |
GO_0002764 | Biological process | immune response-regulating signaling pathway |
GO_0140105 | Biological process | interleukin-10-mediated signaling pathway |
GO_0070821 | Cellular component | tertiary granule membrane |
GO_0005576 | Cellular component | extracellular region |
GO_0035579 | Cellular component | specific granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
GO_0032396 | Molecular function | inhibitory MHC class I receptor activity |
Gene name | LILRA3 |
Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 3 LILRA3 protein Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e) Leukocyte immunoglobulin-like receptor A3 |
Synonyms | ILT6 LIR4 |
Description | FUNCTION: Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. . |
Accessions | A0A0G2JLV5 ENST00000620589.4 [Q8N6C8-1] ENST00000615416.2 ENST00000619928.1 ENST00000619618.4 ENST00000613983.4 ENST00000620042.4 ENST00000615652.4 [Q8N6C8-1] Q8NHJ5 A0A0G2JM97 ENST00000610381.1 ENST00000617121.1 ENST00000615584.4 ENST00000610305.4 ENST00000612127.4 [Q8N6C8-1] ENST00000619638.4 [Q8N6C8-1] H2B4M3 A0A0G2JM99 A0A0G2JMJ0 H2B4M4 A0A0G2JMY9 ENST00000611439.4 ENST00000613018.4 Q8N6C8 ENST00000616964.3 ENST00000617541.4 [Q8N6C8-2] |