Insufficient scRNA-seq data for expression of LILRA3 at single-cell level.
Insufficient scRNA-seq data for expression of LILRA3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| breast | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| esophagus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| intestine | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lung | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| skin | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| stomach | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| uterus | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0002764 | Biological process | immune response-regulating signaling pathway |
| GO_0140105 | Biological process | interleukin-10-mediated signaling pathway |
| GO_0070821 | Cellular component | tertiary granule membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035579 | Cellular component | specific granule membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
| GO_0032396 | Molecular function | inhibitory MHC class I receptor activity |
| Gene name | LILRA3 |
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 3 LILRA3 protein Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e) Leukocyte immunoglobulin-like receptor A3 |
| Synonyms | ILT6 LIR4 |
| Description | FUNCTION: Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. . |
| Accessions | A0A0G2JLV5 ENST00000620589.4 [Q8N6C8-1] ENST00000615416.2 ENST00000619928.1 ENST00000619618.4 ENST00000613983.4 ENST00000620042.4 ENST00000615652.4 [Q8N6C8-1] Q8NHJ5 A0A0G2JM97 ENST00000610381.1 ENST00000617121.1 ENST00000615584.4 ENST00000610305.4 ENST00000612127.4 [Q8N6C8-1] ENST00000619638.4 [Q8N6C8-1] H2B4M3 A0A0G2JM99 A0A0G2JMJ0 H2B4M4 A0A0G2JMY9 ENST00000611439.4 ENST00000613018.4 Q8N6C8 ENST00000616964.3 ENST00000617541.4 [Q8N6C8-2] |