HLA-DMB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2001190Biological processpositive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO_0019886Biological processantigen processing and presentation of exogenous peptide antigen via MHC class II
GO_0002250Biological processadaptive immune response
GO_0050870Biological processpositive regulation of T cell activation
GO_0042102Biological processpositive regulation of T cell proliferation
GO_0050778Biological processpositive regulation of immune response
GO_0002399Biological processMHC class II protein complex assembly
GO_0002503Biological processpeptide antigen assembly with MHC class II protein complex
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0031902Cellular componentlate endosome membrane
GO_0042613Cellular componentMHC class II protein complex
GO_0005765Cellular componentlysosomal membrane
GO_0023026Molecular functionMHC class II protein complex binding
GO_0005515Molecular functionprotein binding
GO_0042605Molecular functionpeptide antigen binding

IV. Literature review

[source]
Gene nameHLA-DMB
Protein nameHLA class II histocompatibility antigen, DM beta chain (MHC class II antigen DMB) (Really interesting new gene 7 protein)
MHC class II antigen
Major histocompatibility complex, class II, DM beta
MHC class II HLA-DMB
HLA-DMB
MHC class II antigen HLA-DM beta chain
HLA-DMB (MHC class II antigen)
HLA-DMB protein
HLA class II histocompatibility antigen, DM beta chain
MHC class II antigen beta chain
SynonymsRING7
DMB
DescriptionFUNCTION: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. .

AccessionsA0A140T9C9
ENST00000415927.1
A0A140T9B6
ENST00000428864.6
ENST00000418107.3
ENST00000438310.5
ENST00000440078.6
ENST00000421456.5
ENST00000428420.6
A0A140T9I2
P28068
A0A140T9R2
Q52RG1
A0A0G2JIJ2
A0A1V0E3K4
A0A140T9U6
ENST00000383231.6
ENST00000395312.7
ENST00000413617.6
A0A140T9C6
A0A1V0E3P2
A8CGH8
Q6LEU6
A0A140T946
ENST00000448590.1
ENST00000430099.1
ENST00000447454.6
ENST00000414017.5
A0A1V0E3L6
ENST00000418759.6
A0A140T9T8
ENST00000450897.6
Q29709
ENST00000413696.5
H0Y4B8
ENST00000437583.5
ENST00000438510.5
ENST00000412948.6
A0A140T926
A0A140T987
A0A140T9F5
A0A140T9F6
ENST00000413038.5
A0A140T9Q5
ENST00000440269.5
ENST00000424874.5
A0A1V0E3N8
X5CKA5
ENST00000439344.6
A0A140T9E3
ENST00000449417.1
ENST00000456428.6
ENST00000448798.5
A0A140T9R0
ENST00000441177.5
A0A140T9K0
ENST00000435056.1
ENST00000451921.5
ENST00000430115.5
A0A140T9K4
A0A140T943
A0A140T9K9
ENST00000435204.5
A8CGH7
A0A140T9Q8
ENST00000424822.6
H0Y7A2
ENST00000437382.5
A8CGH9
A0A0G2JI43
ENST00000415090.1
ENST00000452407.6
ENST00000449679.1
A0A140T965
O02952
ENST00000433242.5