CTSH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010813Biological processneuropeptide catabolic process
GO_0010815Biological processbradykinin catabolic process
GO_0045766Biological processpositive regulation of angiogenesis
GO_0033619Biological processmembrane protein proteolysis
GO_0001656Biological processmetanephros development
GO_0010628Biological processpositive regulation of gene expression
GO_0097067Biological processcellular response to thyroid hormone stimulus
GO_0001913Biological processT cell mediated cytotoxicity
GO_0060448Biological processdichotomous subdivision of terminal units involved in lung branching
GO_0031648Biological processprotein destabilization
GO_0031638Biological processzymogen activation
GO_0006955Biological processimmune response
GO_0002250Biological processadaptive immune response
GO_0070371Biological processERK1 and ERK2 cascade
GO_0043066Biological processnegative regulation of apoptotic process
GO_0030335Biological processpositive regulation of cell migration
GO_0006508Biological processproteolysis
GO_0010952Biological processpositive regulation of peptidase activity
GO_0043129Biological processsurfactant homeostasis
GO_0002764Biological processimmune response-regulating signaling pathway
GO_0006915Biological processapoptotic process
GO_0019882Biological processantigen processing and presentation
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0032526Biological processresponse to retinoic acid
GO_0051603Biological processproteolysis involved in protein catabolic process
GO_2001235Biological processpositive regulation of apoptotic signaling pathway
GO_0010634Biological processpositive regulation of epithelial cell migration
GO_0097486Cellular componentmultivesicular body lumen
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0005764Cellular componentlysosome
GO_0070062Cellular componentextracellular exosome
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0034774Cellular componentsecretory granule lumen
GO_0097208Cellular componentalveolar lamellar body
GO_1904724Cellular componenttertiary granule lumen
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0008233Molecular functionpeptidase activity
GO_0004175Molecular functionendopeptidase activity
GO_0008656Molecular functioncysteine-type endopeptidase activator activity involved in apoptotic process
GO_0030108Molecular functionHLA-A specific activating MHC class I receptor activity
GO_0004177Molecular functionaminopeptidase activity
GO_0008234Molecular functioncysteine-type peptidase activity
GO_0004197Molecular functioncysteine-type endopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity
GO_0070324Molecular functionthyroid hormone binding

IV. Literature review

[source]
Gene nameCTSH
Protein namePro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain]
Cathepsin H
Pro-cathepsin H
SynonymsCPSB
DescriptionFUNCTION: Important for the overall degradation of proteins in lysosomes.

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

FUNCTION: Important for the overall degradation of proteins in lysosomes. .

AccessionsENST00000676510.1
ENST00000529861.6
ENST00000615999.5
A0A7I2V2E4
A0A7I2YQ92
ENST00000676763.1
ENST00000679172.1
A0A7I2V673
A0A7I2V3T9
A0A7I2V439
E9PN60
ENST00000677810.1
ENST00000679017.1
A0A3B3IRM7
ENST00000528741.6
A0A7I2YQL1
P09668
ENST00000677011.1
E9PKT6
A0A7I2YQL6
A0A7I2V4N9
ENST00000677936.1
A0A7I2YQX6
ENST00000676880.1
A0A7I2YQH4
A0A7I2V563
ENST00000678799.1
ENST00000678415.1
ENST00000678727.1
ENST00000649928.2
ENST00000528191.6
ENST00000678283.1
ENST00000678487.1
ENST00000677789.1
A0A7I2YQE6
Q6IBC3
ENST00000676808.1
ENST00000678644.1
A0A7I2V314
E9PN84
ENST00000678281.1
ENST00000677921.1
ENST00000677534.1
A0A087X0D5
ENST00000676850.1
A0A7I2V4X5
ENST00000678886.1
A0A7I2V4W0
ENST00000677207.1
A0A7I2V2T8
ENST00000678031.1
ENST00000676639.1
A0A7I2V532
ENST00000677316.1
ENST00000220166.10
ENST00000679211.1
ENST00000679334.1
A0A0B4J217
ENST00000533777.5
ENST00000677320.1
A0A7I2V2L7
ENST00000679047.1
ENST00000525807.6
ENST00000677874.1
A0A7I2V3E8
ENST00000676596.1
A0A7I2V4H2