JSRP1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of JSRP1 at tissue level.

III. Associated gene sets

GO_0003009Biological processskeletal muscle contraction
GO_0060314Biological processregulation of ryanodine-sensitive calcium-release channel activity
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0016529Cellular componentsarcoplasmic reticulum
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameJSRP1
Protein nameJunctional sarcoplasmic reticulum protein 1 (Junctional-face membrane protein of 45 kDa homolog) (JP-45)
SynonymsJP45
DescriptionFUNCTION: Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity. .

AccessionsENST00000300961.10
Q96MG2