Genes | Cell types | No. of supported studies | |
|---|---|---|---|
| Group 1 | 6 studies | ||
| Group 2 | 13 studies | ||
| Group 3 | 49 studies | ||
| Group 4 | 14 studies | ||
| Group 5 | 15 studies |
| Name | germinal center B cell differentiation |
| ID | GO_0002314 |
| collection_id | Biological process |
| Exact synonym | germinal center B lymphocyte differentiation, germinal center B-cell differentiation, germinal center B-lymphocyte differentiation |
| Description | The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). |
| Related synonym | germinal center B cell development |
| Comment | Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. |
| External URL | |
| Genes |