Name | germinal center B cell differentiation |
ID | GO_0002314 |
collection_id | Biological process |
Exact synonym | germinal center B lymphocyte differentiation, germinal center B-cell differentiation, germinal center B-lymphocyte differentiation |
Description | The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). |
Related synonym | germinal center B cell development |
Comment | Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. |
External URL | |
Genes |