post-translational protein targeting to endoplasmic reticulum membrane

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 19 studies
Group 28 studies
Group 34 studies
Group 427 studies

II. Literature review

[source]
Namepost-translational protein targeting to endoplasmic reticulum membrane
IDGO_0006620
collection_id

Biological process

Exact synonym

SRP-independent endoplasmic reticulum protein-membrane targeting, posttranslational endoplasmic reticulum membrane targeting, posttranslational endoplasmic reticulum protein-membrane targeting, posttranslational protein endoplasmic reticulum membrane targeting, posttranslational protein targeting to ER membrane, posttranslational protein targeting to endoplasmic reticulum membrane

Description

The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.

External URL
Genes