ILDR2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030073Biological processinsulin secretion
GO_0043484Biological processregulation of RNA splicing
GO_0050868Biological processnegative regulation of T cell activation
GO_0030154Biological processcell differentiation
GO_0031016Biological processpancreas development
GO_0009749Biological processresponse to glucose
GO_0048873Biological processhomeostasis of number of cells within a tissue
GO_0070160Cellular componenttight junction
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005923Cellular componentbicellular tight junction
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameILDR2
Protein nameImmunoglobulin like domain containing receptor 2
Immunoglobulin-like domain-containing receptor 2 (Angulin-3)
SynonymsC1orf32
DescriptionFUNCTION: May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions (By similarity). Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity . In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1 (By similarity). .

AccessionsENST00000271417.8
Q71H61
E9PQC8
E9PPL0
E9PNU3
E9PLS0
E9PR23
ENST00000529071.5
ENST00000469934.6
ENST00000529387.5
ENST00000528703.5
ENST00000526687.1
ENST00000525740.5
E9PRA4