Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal rod cell | 9 studies | 50% ± 13% | |
| retinal cone cell | 8 studies | 59% ± 23% | |
| retinal pigment epithelial cell | 4 studies | 30% ± 8% | |
| retinal bipolar neuron | 3 studies | 33% ± 4% | |
| rod bipolar cell | 3 studies | 23% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 7 studies | 35% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 93% | 14.01 | 211 / 226 | 0% | 0 | 0 / 406 |
| ovary | 67% | 1.53 | 121 / 180 | 0% | 0 | 0 / 430 |
| thymus | 64% | 1.23 | 421 / 653 | 0% | 0 | 0 / 605 |
| uterus | 63% | 1.47 | 107 / 170 | 0% | 0 | 0 / 459 |
| prostate | 62% | 1.21 | 151 / 245 | 0% | 0.03 | 1 / 502 |
| lung | 60% | 1.06 | 347 / 578 | 0% | 0.02 | 5 / 1155 |
| adrenal gland | 58% | 1.22 | 149 / 258 | 0% | 0 | 0 / 230 |
| brain | 58% | 1.41 | 1520 / 2642 | 0% | 0.01 | 1 / 705 |
| breast | 57% | 1.08 | 262 / 459 | 0% | 0.00 | 1 / 1118 |
| intestine | 56% | 1.00 | 542 / 966 | 1% | 0.01 | 5 / 527 |
| blood vessel | 56% | 1.08 | 746 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 54% | 0.95 | 782 / 1445 | 1% | 0.03 | 2 / 183 |
| spleen | 54% | 1.26 | 131 / 241 | 0% | 0 | 0 / 0 |
| adipose | 54% | 0.95 | 649 / 1204 | 0% | 0 | 0 / 0 |
| skin | 54% | 1.72 | 972 / 1809 | 0% | 0 | 0 / 472 |
| kidney | 53% | 1.03 | 47 / 89 | 1% | 0.04 | 6 / 901 |
| stomach | 48% | 0.86 | 174 / 359 | 3% | 0.05 | 8 / 286 |
| peripheral blood | 49% | 0.90 | 455 / 929 | 0% | 0 | 0 / 0 |
| bladder | 43% | 0.95 | 9 / 21 | 0% | 0 | 0 / 504 |
| heart | 42% | 0.64 | 361 / 861 | 0% | 0 | 0 / 0 |
| muscle | 39% | 0.68 | 315 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 39% | 0.65 | 128 / 328 | 0% | 0 | 0 / 178 |
| eye | 0% | 0 | 0 / 0 | 10% | 2.93 | 8 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007601 | Biological process | visual perception |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0007399 | Biological process | nervous system development |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0016922 | Molecular function | nuclear receptor binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0043522 | Molecular function | leucine zipper domain binding |
| GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0001216 | Molecular function | DNA-binding transcription activator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CRX |
| Protein name | Cone-rod homeobox protein Cone-rod homeobox |
| Synonyms | CORD2 |
| Description | FUNCTION: Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. . |
| Accessions | A4GUB7 ENST00000613299.1 H3BUU7 O43186 ENST00000566686.5 ENST00000221996.12 A0A087WTS9 |