Insufficient scRNA-seq data for expression of NKX2-6 at single-cell level.
Insufficient scRNA-seq data for expression of NKX2-6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
heart | 60% | 18.03 | 518 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 20% | 1.77 | 9 / 45 |
skin | 7% | 0.65 | 121 / 1809 | 11% | 0.69 | 50 / 472 |
prostate | 13% | 0.89 | 31 / 245 | 2% | 0.07 | 11 / 502 |
esophagus | 5% | 0.93 | 76 / 1445 | 5% | 0.14 | 10 / 183 |
uterus | 1% | 0.13 | 2 / 170 | 2% | 0.13 | 11 / 459 |
intestine | 3% | 0.20 | 31 / 966 | 0% | 0.00 | 1 / 527 |
thymus | 3% | 0.13 | 20 / 653 | 0% | 0 | 0 / 605 |
lung | 2% | 0.09 | 10 / 578 | 1% | 0.07 | 14 / 1155 |
peripheral blood | 3% | 0.15 | 26 / 929 | 0% | 0 | 0 / 0 |
adipose | 2% | 0.10 | 28 / 1204 | 0% | 0 | 0 / 0 |
breast | 2% | 0.10 | 7 / 459 | 1% | 0.02 | 8 / 1118 |
pancreas | 1% | 0.02 | 2 / 328 | 1% | 0.02 | 2 / 178 |
adrenal gland | 0% | 0.01 | 1 / 258 | 1% | 0.11 | 2 / 230 |
kidney | 1% | 0.17 | 1 / 89 | 0% | 0.01 | 1 / 901 |
blood vessel | 1% | 0.05 | 16 / 1335 | 0% | 0 | 0 / 0 |
stomach | 1% | 0.02 | 2 / 359 | 0% | 0.00 | 1 / 286 |
spleen | 1% | 0.05 | 2 / 241 | 0% | 0 | 0 / 0 |
ovary | 1% | 0.02 | 1 / 180 | 0% | 0.01 | 1 / 430 |
brain | 0% | 0.03 | 12 / 2642 | 0% | 0.00 | 1 / 705 |
liver | 0% | 0 | 0 / 226 | 0% | 0.05 | 2 / 406 |
bladder | 0% | 0 | 0 / 21 | 0% | 0.01 | 2 / 504 |
muscle | 0% | 0.01 | 2 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0055014 | Biological process | atrial cardiac muscle cell development |
GO_0050673 | Biological process | epithelial cell proliferation |
GO_0055015 | Biological process | ventricular cardiac muscle cell development |
GO_0060037 | Biological process | pharyngeal system development |
GO_0060039 | Biological process | pericardium development |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0043586 | Biological process | tongue development |
GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0030154 | Biological process | cell differentiation |
GO_0035050 | Biological process | embryonic heart tube development |
GO_1904036 | Biological process | negative regulation of epithelial cell apoptotic process |
GO_1904019 | Biological process | epithelial cell apoptotic process |
GO_0048565 | Biological process | digestive tract development |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0021854 | Biological process | hypothalamus development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
Gene name | NKX2-6 |
Protein name | Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F) |
Synonyms | NKX2F |
Description | FUNCTION: Acts as a transcriptional activator . In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development. . |
Accessions | A6NCS4 ENST00000325017.4 |