NKX3-2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of NKX3-2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	90%	1665.57	871 / 966	49%	1.38	260 / 527
stomach	46%	225.24	166 / 359	56%	2.27	160 / 286
uterus	68%	107.16	116 / 170	31%	1.93	141 / 459
spleen	98%	273.72	237 / 241	0%	0	0 / 0
pancreas	14%	7.96	45 / 328	81%	4.45	144 / 178
esophagus	63%	241.56	910 / 1445	30%	0.76	54 / 183
ovary	44%	53.66	80 / 180	41%	2.00	176 / 430
prostate	46%	59.47	113 / 245	21%	1.17	106 / 502
breast	12%	8.82	54 / 459	52%	1.67	579 / 1118
thymus	40%	33.12	263 / 653	20%	0.86	119 / 605
skin	9%	5.36	158 / 1809	50%	1.62	237 / 472
adipose	47%	119.08	563 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	40%	1.25	18 / 45
lung	3%	2.10	16 / 578	33%	1.56	383 / 1155
lymph node	0%	0	0 / 0	34%	0.54	10 / 29
bladder	0%	0	0 / 21	32%	0.95	160 / 504
brain	0%	0.24	12 / 2642	27%	1.21	187 / 705
adrenal gland	7%	3.62	17 / 258	18%	1.17	41 / 230
liver	0%	0	0 / 226	9%	0.25	35 / 406
blood vessel	9%	5.07	114 / 1335	0%	0	0 / 0
kidney	2%	0.83	2 / 89	3%	0.12	27 / 901
heart	0%	0.22	3 / 861	0%	0	0 / 0
muscle	0%	0.05	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006366	Biological process	transcription by RNA polymerase II
GO_0031016	Biological process	pancreas development
GO_0007368	Biological process	determination of left/right symmetry
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0048645	Biological process	animal organ formation
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0048536	Biological process	spleen development
GO_0032331	Biological process	negative regulation of chondrocyte differentiation
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0048706	Biological process	embryonic skeletal system development
GO_0060576	Biological process	intestinal epithelial cell development
GO_0030154	Biological process	cell differentiation
GO_0001501	Biological process	skeletal system development
GO_0042474	Biological process	middle ear morphogenesis
GO_0048705	Biological process	skeletal system morphogenesis
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001227	Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0005515	Molecular function	protein binding

Gene name	NKX3-2
Protein name	Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B)
Synonyms	NKX3B BAPX1
Description	FUNCTION: Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). .
Accessions	P78367 ENST00000382438.6

NKX3-2 report