FOXE1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FOXE1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	13044.15	652 / 653	96%	260.97	583 / 605
tonsil	0%	0	0 / 0	96%	92.27	43 / 45
esophagus	39%	316.59	564 / 1445	49%	70.35	89 / 183
skin	47%	67.01	849 / 1809	1%	0.18	4 / 472
uterus	2%	8.85	3 / 170	38%	17.75	176 / 459
lung	5%	5.46	28 / 578	33%	34.12	386 / 1155
prostate	29%	27.13	70 / 245	0%	0.05	1 / 502
kidney	7%	4.45	6 / 89	1%	0.24	9 / 901
bladder	0%	0	0 / 21	7%	2.99	36 / 504
ovary	0%	0	0 / 180	2%	0.69	10 / 430
adrenal gland	0%	0	0 / 258	2%	0.48	4 / 230
intestine	0%	0.43	4 / 966	1%	0.27	6 / 527
pancreas	1%	4.43	3 / 328	1%	0.09	1 / 178
stomach	1%	1.15	5 / 359	0%	0	0 / 286
adipose	1%	0.98	11 / 1204	0%	0	0 / 0
muscle	1%	0.69	6 / 803	0%	0	0 / 0
breast	1%	0.26	3 / 459	0%	0.01	1 / 1118
brain	0%	0.73	6 / 2642	0%	0.08	3 / 705
heart	0%	0.34	4 / 861	0%	0	0 / 0
blood vessel	0%	0.40	6 / 1335	0%	0	0 / 0
spleen	0%	0.52	1 / 241	0%	0	0 / 0
peripheral blood	0%	0.28	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1904888	Biological process	cranial skeletal system development
GO_0006590	Biological process	thyroid hormone generation
GO_0048562	Biological process	embryonic organ morphogenesis
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0031069	Biological process	hair follicle morphogenesis
GO_0030878	Biological process	thyroid gland development
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0060023	Biological process	soft palate development
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030154	Biological process	cell differentiation
GO_0048538	Biological process	thymus development
GO_0160093	Biological process	chordate pharynx development
GO_0009653	Biological process	anatomical structure morphogenesis
GO_0060022	Biological process	hard palate development
GO_0016477	Biological process	cell migration
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565	Molecular function	sequence-specific DNA binding
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding

Gene name	FOXE1
Protein name	Forkhead box protein E1 (Forkhead box protein E2) (Forkhead-related protein FKHL15) (HFKH4) (HNF-3/fork head-like protein 5) (HFKL5) (Thyroid transcription factor 2) (TTF-2)
Synonyms	FKHL15 FOXE2 TITF2 TTF2
Description	FUNCTION: Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. .
Accessions	ENST00000375123.5 O00358

FOXE1 report