ELF5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ELF5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ELF5 at tissue level.

III. Associated gene sets

GO_0030154Biological processcell differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameELF5
Protein nameETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)
E74 like ETS transcription factor 5
E74-like factor 5 (Ets domain transcription factor), isoform CRA_a (cDNA FLJ78106, highly similar to Homo sapiens E74-like factor 5 (ets domain transcription factor) (ELF5), transcript variant 2, mRNA) (cDNA FLJ90716 fis, clone PLACE1008549, highly similar to ETS-related transcription factor Elf-5) (cDNA, FLJ92906, Homo sapiens E74-like factor 5 (ets domain transcription factor)(ELF5), mRNA)
SynonymsESE2
hCG_28585
DescriptionFUNCTION: Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. .; FUNCTION: Isoform 2 binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT]. Transcriptionally activates SPRR2A and the parotid gland-specific PSP promoters. .

AccessionsENST00000257832.7 [Q9UKW6-2]
A0A087X1W9
ENST00000429939.6 [Q9UKW6-4]
ENST00000673820.1
ENST00000532417.1 [Q9UKW6-3]
A8K443
ENST00000620316.4
A0A669KB78
ENST00000312319.6 [Q9UKW6-1]
Q9UKW6