BNC1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BNC1 at tissue level.

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0007283Biological processspermatogenesis
GO_0008544Biological processepidermis development
GO_1900195Biological processpositive regulation of oocyte maturation
GO_0030154Biological processcell differentiation
GO_0006356Biological processregulation of transcription by RNA polymerase I
GO_0045943Biological processpositive regulation of transcription by RNA polymerase I
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0001216Molecular functionDNA-binding transcription activator activity
GO_0000182Molecular functionrDNA binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameBNC1
Protein nameBasonuclin 1
Zinc finger protein basonuclin-1
SynonymsBNC
DescriptionFUNCTION: Transcriptional activator (By similarity). It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles . Required for the maintenance of spermatogenesis (By similarity). It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade . May also play a role in the early development of embryos (By similarity). .

AccessionsENST00000569704.2
F5GY04
ENST00000345382.7
Q01954