Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 28% ± 11% | |
glutamatergic neuron | 6 studies | 42% ± 23% | |
GABAergic neuron | 6 studies | 40% ± 20% | |
astrocyte | 6 studies | 28% ± 8% | |
oligodendrocyte | 6 studies | 24% ± 6% | |
neuron | 4 studies | 25% ± 9% | |
microglial cell | 4 studies | 21% ± 3% | |
epithelial cell | 4 studies | 30% ± 8% | |
amacrine cell | 4 studies | 18% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 27% ± 7% | |
fibroblast | 4 studies | 21% ± 8% | |
macrophage | 4 studies | 21% ± 4% | |
type I pneumocyte | 4 studies | 24% ± 6% | |
interneuron | 4 studies | 44% ± 21% | |
GABAergic interneuron | 3 studies | 18% ± 3% | |
retinal bipolar neuron | 3 studies | 21% ± 3% | |
cardiac muscle cell | 3 studies | 20% ± 2% | |
ciliated cell | 3 studies | 19% ± 0% | |
retinal rod cell | 3 studies | 19% ± 3% | |
rod bipolar cell | 3 studies | 25% ± 5% | |
endothelial cell of lymphatic vessel | 3 studies | 21% ± 4% | |
transit amplifying cell | 3 studies | 33% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2072.76 | 21 / 21 | 100% | 11.04 | 504 / 504 |
esophagus | 100% | 2193.80 | 1445 / 1445 | 100% | 12.15 | 183 / 183 |
lung | 100% | 2470.49 | 578 / 578 | 100% | 10.49 | 1155 / 1155 |
thymus | 100% | 3334.81 | 653 / 653 | 100% | 12.67 | 604 / 605 |
ovary | 100% | 2358.03 | 180 / 180 | 100% | 9.62 | 429 / 430 |
intestine | 100% | 2106.56 | 966 / 966 | 100% | 11.33 | 525 / 527 |
adrenal gland | 100% | 2451.60 | 258 / 258 | 100% | 9.16 | 229 / 230 |
uterus | 100% | 2802.96 | 170 / 170 | 100% | 11.10 | 457 / 459 |
pancreas | 100% | 1166.07 | 328 / 328 | 99% | 11.04 | 177 / 178 |
brain | 99% | 1888.07 | 2625 / 2642 | 100% | 11.82 | 705 / 705 |
stomach | 99% | 1287.19 | 357 / 359 | 100% | 11.52 | 285 / 286 |
prostate | 100% | 2055.53 | 245 / 245 | 99% | 7.32 | 497 / 502 |
kidney | 100% | 1612.44 | 89 / 89 | 99% | 10.09 | 892 / 901 |
breast | 100% | 2187.88 | 459 / 459 | 99% | 9.05 | 1106 / 1118 |
liver | 100% | 1607.22 | 226 / 226 | 99% | 7.22 | 400 / 406 |
skin | 100% | 1615.84 | 1809 / 1809 | 96% | 7.41 | 451 / 472 |
adipose | 100% | 2094.47 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 2734.68 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.28 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.88 | 1 / 1 |
blood vessel | 100% | 1948.62 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2185.94 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 1564.60 | 850 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 7.67 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 90% | 6.59 | 72 / 80 |
peripheral blood | 43% | 478.60 | 402 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0048386 | Biological process | positive regulation of retinoic acid receptor signaling pathway |
GO_0030522 | Biological process | intracellular receptor signaling pathway |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0030154 | Biological process | cell differentiation |
GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
GO_0048856 | Biological process | anatomical structure development |
GO_0005654 | Cellular component | nucleoplasm |
GO_0016605 | Cellular component | PML body |
GO_0000785 | Cellular component | chromatin |
GO_0003677 | Molecular function | DNA binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003707 | Molecular function | nuclear steroid receptor activity |
GO_0004879 | Molecular function | nuclear receptor activity |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0042826 | Molecular function | histone deacetylase binding |
Gene name | NR2C1 |
Protein name | Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) Nuclear receptor subfamily 2, group C isoform |
Synonyms | hCG_18174 TR2 |
Description | FUNCTION: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation. . |
Accessions | ENST00000393101.7 [P13056-2] P13056 H0YIV1 ENST00000622476.4 H0YHC6 ENST00000551647.5 ENST00000333003.10 [P13056-1] B6ZGT7 H9NIM2 ENST00000547469.1 ENST00000330677.7 [P13056-3] ENST00000552791.1 A0A087WUK4 F8W1Q1 |