Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 23% ± 7% | |
pericyte | 6 studies | 21% ± 3% | |
fibroblast | 4 studies | 19% ± 2% | |
epithelial cell | 3 studies | 30% ± 12% | |
smooth muscle cell | 3 studies | 20% ± 4% | |
endothelial cell of vascular tree | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of ERF at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 4437.46 | 180 / 180 | 100% | 127.11 | 430 / 430 |
uterus | 100% | 5046.41 | 170 / 170 | 100% | 75.81 | 457 / 459 |
intestine | 100% | 3678.48 | 966 / 966 | 99% | 60.49 | 523 / 527 |
thymus | 100% | 4442.37 | 652 / 653 | 99% | 50.51 | 601 / 605 |
stomach | 100% | 2629.12 | 359 / 359 | 99% | 65.80 | 283 / 286 |
skin | 100% | 3410.09 | 1809 / 1809 | 99% | 97.43 | 467 / 472 |
esophagus | 100% | 3121.45 | 1445 / 1445 | 99% | 64.11 | 181 / 183 |
adrenal gland | 100% | 3190.61 | 258 / 258 | 99% | 66.27 | 227 / 230 |
kidney | 100% | 3634.60 | 89 / 89 | 98% | 49.66 | 887 / 901 |
bladder | 100% | 3127.33 | 21 / 21 | 98% | 53.85 | 496 / 504 |
breast | 100% | 3959.00 | 459 / 459 | 98% | 52.99 | 1100 / 1118 |
prostate | 100% | 3517.71 | 245 / 245 | 98% | 35.29 | 493 / 502 |
brain | 98% | 2029.29 | 2592 / 2642 | 100% | 78.19 | 705 / 705 |
liver | 100% | 2449.46 | 226 / 226 | 98% | 51.28 | 398 / 406 |
lung | 100% | 4411.89 | 577 / 578 | 98% | 53.29 | 1127 / 1155 |
pancreas | 96% | 1584.83 | 316 / 328 | 98% | 57.71 | 175 / 178 |
adipose | 100% | 3823.89 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3972.84 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 72.83 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 36.61 | 29 / 29 |
spleen | 100% | 3406.16 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 64.48 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 40.63 | 1 / 1 |
heart | 100% | 2569.95 | 857 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 3825.64 | 923 / 929 | 0% | 0 | 0 / 0 |
muscle | 48% | 417.52 | 389 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030154 | Biological process | cell differentiation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
Gene name | ERF |
Protein name | ETS2 repressor factor ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2) |
Synonyms | |
Description | FUNCTION: Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity). . |
Accessions | ENST00000440177.6 [P50548-2] M0QX79 ENST00000593944.5 P50548 ENST00000222329.9 [P50548-1] ENST00000598965.1 M0QXN0 |