Insufficient scRNA-seq data for expression of FOXB1 at single-cell level.
Insufficient scRNA-seq data for expression of FOXB1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 35% | 80.84 | 923 / 2642 | 4% | 0.17 | 27 / 705 |
ovary | 11% | 1.62 | 20 / 180 | 16% | 2.18 | 70 / 430 |
lymph node | 0% | 0 | 0 / 0 | 14% | 0.28 | 4 / 29 |
lung | 1% | 0.18 | 6 / 578 | 12% | 0.59 | 143 / 1155 |
uterus | 3% | 1.28 | 5 / 170 | 10% | 0.43 | 47 / 459 |
bladder | 0% | 0 | 0 / 21 | 5% | 0.57 | 24 / 504 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.25 | 2 / 45 |
skin | 0% | 0.06 | 7 / 1809 | 4% | 0.32 | 18 / 472 |
pancreas | 0% | 0 | 0 / 328 | 4% | 0.11 | 7 / 178 |
esophagus | 0% | 0 | 0 / 1445 | 3% | 0.07 | 5 / 183 |
adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.26 | 5 / 230 |
intestine | 1% | 0.10 | 6 / 966 | 2% | 0.03 | 8 / 527 |
stomach | 1% | 0.08 | 2 / 359 | 1% | 0.02 | 4 / 286 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.05 | 13 / 901 |
thymus | 1% | 0.18 | 6 / 653 | 0% | 0.01 | 3 / 605 |
prostate | 0% | 0.07 | 1 / 245 | 1% | 0.02 | 5 / 502 |
peripheral blood | 1% | 0.11 | 8 / 929 | 0% | 0 | 0 / 0 |
spleen | 1% | 0.10 | 2 / 241 | 0% | 0 | 0 / 0 |
breast | 0% | 0.07 | 1 / 459 | 0% | 0.02 | 5 / 1118 |
liver | 0% | 0 | 0 / 226 | 0% | 0.00 | 1 / 406 |
adipose | 0% | 0.02 | 2 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0.02 | 2 / 1335 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.02 | 1 / 803 | 0% | 0 | 0 / 0 |
heart | 0% | 0.01 | 1 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0021794 | Biological process | thalamus development |
GO_0061377 | Biological process | mammary gland lobule development |
GO_0021510 | Biological process | spinal cord development |
GO_0001655 | Biological process | urogenital system development |
GO_0021855 | Biological process | hypothalamus cell migration |
GO_0021767 | Biological process | mammillary body development |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0033504 | Biological process | floor plate development |
GO_0061030 | Biological process | epithelial cell differentiation involved in mammary gland alveolus development |
GO_0008542 | Biological process | visual learning |
GO_0061379 | Biological process | inferior colliculus development |
GO_0030154 | Biological process | cell differentiation |
GO_0001756 | Biological process | somitogenesis |
GO_0007412 | Biological process | axon target recognition |
GO_0009653 | Biological process | anatomical structure morphogenesis |
GO_0007595 | Biological process | lactation |
GO_0061374 | Biological process | mammillothalamic axonal tract development |
GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
GO_0022029 | Biological process | telencephalon cell migration |
GO_0030901 | Biological process | midbrain development |
GO_0061381 | Biological process | cell migration in diencephalon |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | FOXB1 |
Protein name | Forkhead box protein B1 (Transcription factor FKH-5) |
Synonyms | FKH5 |
Description | FUNCTION: Transcription factor expressed by neural progenitor cells in specific regions of the embryonic neuroepithelium. Essential for the mammillary nuclei maintenance. Negatively regulates the proliferation of oligodendrocyte progenitors and promotes oligodendrocyte maturation. Also expressed in mammary glands, plays a role in lactation, controls development of mammary glands and the inferior colliculi of the midbrain in the central nervous system that regulates the milk-ejection reflex. . |
Accessions | Q99853 ENST00000396057.6 |