ELF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	39 studies	37% ± 17%	Explore
fibroblast	24 studies	30% ± 14%	Explore
natural killer cell	18 studies	24% ± 7%	Explore
macrophage	17 studies	38% ± 19%	Explore
oligodendrocyte	16 studies	49% ± 18%	Explore
astrocyte	16 studies	35% ± 16%	Explore
smooth muscle cell	15 studies	27% ± 12%	Explore
pericyte	15 studies	30% ± 12%	Explore
endothelial cell of lymphatic vessel	14 studies	36% ± 16%	Explore
oligodendrocyte precursor cell	14 studies	34% ± 17%	Explore
B cell	13 studies	24% ± 9%	Explore
microglial cell	13 studies	44% ± 13%	Explore
non-classical monocyte	12 studies	28% ± 14%	Explore
classical monocyte	11 studies	23% ± 9%	Explore
glutamatergic neuron	11 studies	40% ± 24%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	26% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	26% ± 8%	Explore
capillary endothelial cell	11 studies	23% ± 9%	Explore
mast cell	11 studies	26% ± 10%	Explore
GABAergic neuron	10 studies	45% ± 19%	Explore
epithelial cell	10 studies	37% ± 20%	Explore
plasmacytoid dendritic cell	10 studies	24% ± 7%	Explore
monocyte	9 studies	39% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	20% ± 5%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 5%	Explore
myeloid cell	9 studies	33% ± 11%	Explore
adipocyte	9 studies	33% ± 11%	Explore
dendritic cell	9 studies	39% ± 16%	Explore
T cell	8 studies	24% ± 7%	Explore
naive B cell	8 studies	20% ± 5%	Explore
CD4-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
basal cell	8 studies	30% ± 18%	Explore
endothelial cell of artery	8 studies	23% ± 6%	Explore
vein endothelial cell	8 studies	28% ± 16%	Explore
ciliated cell	8 studies	34% ± 12%	Explore
mature NK T cell	7 studies	21% ± 6%	Explore
mucosal invariant T cell	7 studies	22% ± 4%	Explore
endothelial cell of vascular tree	7 studies	31% ± 18%	Explore
type I pneumocyte	7 studies	33% ± 13%	Explore
gamma-delta T cell	7 studies	23% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
neuron	6 studies	46% ± 22%	Explore
interneuron	6 studies	51% ± 21%	Explore
retinal ganglion cell	6 studies	46% ± 21%	Explore
lymphocyte	6 studies	24% ± 6%	Explore
regulatory T cell	6 studies	18% ± 2%	Explore
retina horizontal cell	6 studies	46% ± 17%	Explore
retinal cone cell	6 studies	29% ± 9%	Explore
retinal rod cell	6 studies	27% ± 9%	Explore
mesothelial cell	6 studies	34% ± 10%	Explore
Mueller cell	6 studies	35% ± 13%	Explore
myofibroblast cell	6 studies	28% ± 12%	Explore
leukocyte	5 studies	24% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	20% ± 5%	Explore
memory B cell	5 studies	18% ± 3%	Explore
amacrine cell	5 studies	36% ± 11%	Explore
cardiac muscle cell	5 studies	40% ± 11%	Explore
connective tissue cell	5 studies	24% ± 9%	Explore
club cell	5 studies	29% ± 10%	Explore
type II pneumocyte	5 studies	32% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	20% ± 3%	Explore
glial cell	4 studies	31% ± 5%	Explore
granule cell	4 studies	32% ± 6%	Explore
retinal bipolar neuron	4 studies	24% ± 5%	Explore
mononuclear phagocyte	4 studies	30% ± 11%	Explore
ON-bipolar cell	4 studies	31% ± 10%	Explore
neutrophil	4 studies	23% ± 6%	Explore
goblet cell	4 studies	37% ± 21%	Explore
conventional dendritic cell	3 studies	36% ± 12%	Explore
GABAergic interneuron	3 studies	32% ± 8%	Explore
progenitor cell	3 studies	33% ± 3%	Explore
precursor B cell	3 studies	26% ± 3%	Explore
pro-B cell	3 studies	26% ± 4%	Explore
immature B cell	3 studies	25% ± 8%	Explore
GABAergic amacrine cell	3 studies	39% ± 5%	Explore
OFF-bipolar cell	3 studies	36% ± 4%	Explore
glycinergic amacrine cell	3 studies	39% ± 2%	Explore
rod bipolar cell	3 studies	32% ± 9%	Explore
innate lymphoid cell	3 studies	20% ± 3%	Explore
hepatocyte	3 studies	60% ± 24%	Explore
neural progenitor cell	3 studies	43% ± 18%	Explore
ependymal cell	3 studies	43% ± 12%	Explore
alveolar macrophage	3 studies	48% ± 11%	Explore
respiratory goblet cell	3 studies	33% ± 12%	Explore
Schwann cell	3 studies	36% ± 7%	Explore
muscle cell	3 studies	44% ± 22%	Explore
transit amplifying cell	3 studies	43% ± 33%	Explore
mural cell	3 studies	41% ± 9%	Explore
abnormal cell	3 studies	32% ± 18%	Explore
mucus secreting cell	3 studies	30% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	43% ± 19%	Explore
peripheral blood	10 studies	24% ± 9%	Explore
lung	9 studies	27% ± 9%	Explore
eye	7 studies	38% ± 16%	Explore
heart	5 studies	36% ± 12%	Explore
liver	4 studies	37% ± 16%	Explore
intestine	4 studies	20% ± 3%	Explore
adipose	4 studies	35% ± 12%	Explore
bone marrow	3 studies	23% ± 10%	Explore
kidney	3 studies	25% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	2702.71	21 / 21	100%	11.45	504 / 504
esophagus	100%	2806.20	1445 / 1445	100%	14.82	183 / 183
lung	100%	2882.55	578 / 578	100%	12.67	1155 / 1155
ovary	100%	2634.74	180 / 180	100%	11.01	430 / 430
breast	100%	3292.89	459 / 459	100%	18.55	1116 / 1118
prostate	100%	3140.10	245 / 245	100%	17.28	501 / 502
intestine	100%	2941.27	966 / 966	100%	10.60	525 / 527
uterus	100%	3044.11	170 / 170	99%	15.25	456 / 459
brain	99%	1671.75	2623 / 2642	100%	12.40	704 / 705
thymus	100%	2984.65	653 / 653	99%	15.01	599 / 605
stomach	100%	1999.98	359 / 359	99%	11.34	283 / 286
pancreas	100%	1373.34	328 / 328	99%	12.29	176 / 178
kidney	100%	1796.52	89 / 89	97%	11.34	877 / 901
adrenal gland	100%	1735.16	258 / 258	97%	10.14	223 / 230
skin	100%	2576.75	1809 / 1809	92%	10.14	436 / 472
liver	100%	1266.74	226 / 226	84%	5.77	342 / 406
adipose	100%	3343.26	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3197.88	1335 / 1335	0%	0	0 / 0
muscle	100%	2107.38	803 / 803	0%	0	0 / 0
spleen	100%	2843.21	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	14.67	45 / 45
ureter	0%	0	0 / 0	100%	4.25	1 / 1
heart	99%	1659.71	853 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	9.38	28 / 29
peripheral blood	94%	1795.67	875 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	68%	5.29	54 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030154	Biological process	cell differentiation
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]

Gene name	ELF2
Protein name	E74 like ETS transcription factor 2 E74-like factor 2 (Ets domain transcription factor), isoform CRA_b (cDNA FLJ53930, highly similar to ETS-related transcription factor Elf-2) (cDNA, FLJ79354, highly similar to ETS-related transcription factor Elf-2) ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)
Synonyms	NERF hCG_1641148
Description	FUNCTION: Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.; FUNCTION: Isoform 2 may function in repression of RUNX1-mediated transactivation.
Accessions	Q15723 B7Z720 ENST00000510408.5 [Q15723-2] ENST00000379549.7 [Q15723-4] D6RHI1 ENST00000379550.5 [Q15723-5] ENST00000686138.1 [Q15723-5] ENST00000511184.5 ENST00000358635.7 [Q15723-3] ENST00000394235.6 [Q15723-1] ENST00000512627.1 D6RGD9

ELF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review