UNC45B | OmnibusX

Name	Number of supported studies	Average coverage
cardiac muscle cell	3 studies	18% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of UNC45B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
muscle	100%	16965.84	803 / 803	0%	0	0 / 0
heart	98%	11078.12	841 / 861	0%	0	0 / 0
spleen	30%	108.95	72 / 241	0%	0	0 / 0
lung	20%	100.94	115 / 578	2%	0.08	20 / 1155
stomach	13%	63.26	45 / 359	5%	0.08	13 / 286
blood vessel	15%	267.39	206 / 1335	0%	0	0 / 0
prostate	6%	66.26	14 / 245	6%	0.51	31 / 502
tonsil	0%	0	0 / 0	7%	0.53	3 / 45
uterus	0%	0	0 / 170	5%	3.78	22 / 459
lymph node	0%	0	0 / 0	3%	0.04	1 / 29
esophagus	2%	13.71	24 / 1445	1%	0.01	1 / 183
kidney	1%	3.88	1 / 89	1%	0.02	9 / 901
breast	1%	11.75	5 / 459	0%	0.03	5 / 1118
thymus	1%	4.92	4 / 653	0%	0.02	3 / 605
peripheral blood	1%	5.27	9 / 929	0%	0	0 / 0
skin	0%	6.92	5 / 1809	0%	0.01	2 / 472
adipose	1%	2.60	7 / 1204	0%	0	0 / 0
intestine	0%	4.21	1 / 966	0%	0.01	2 / 527
ovary	0%	0	0 / 180	0%	0.01	2 / 430
bladder	0%	0	0 / 21	0%	0.01	2 / 504
adrenal gland	0%	2.28	1 / 258	0%	0	0 / 230
brain	0%	0.32	3 / 2642	0%	0.02	1 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
pancreas	0%	0	0 / 328	0%	0	0 / 178
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002088	Biological process	lens development in camera-type eye
GO_0030154	Biological process	cell differentiation
GO_0061077	Biological process	chaperone-mediated protein folding
GO_0007517	Biological process	muscle organ development
GO_0005829	Cellular component	cytosol
GO_0030018	Cellular component	Z disc
GO_0031672	Cellular component	A band
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005515	Molecular function	protein binding
GO_0051879	Molecular function	Hsp90 protein binding

Gene name	UNC45B
Protein name	Unc-45 myosin chaperone B Protein unc-45 homolog B (Unc-45B) (SMUNC45)
Synonyms	CMYA4 UNC45
Description	FUNCTION: Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. .
Accessions	ENST00000268876.9 [Q8IWX7-1] ENST00000591048.2 [Q8IWX7-2] A0A1B1PFW5 Q8IWX7 ENST00000394570.7 [Q8IWX7-3]

UNC45B report