INSC | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of INSC at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	517.61	964 / 966	50%	1.34	265 / 527
pancreas	88%	72.06	289 / 328	62%	3.58	110 / 178
stomach	94%	169.84	337 / 359	44%	1.02	125 / 286
bladder	81%	101.62	17 / 21	23%	0.76	117 / 504
esophagus	72%	195.30	1043 / 1445	26%	0.71	48 / 183
prostate	93%	151.33	228 / 245	4%	0.07	21 / 502
lung	75%	101.04	434 / 578	10%	0.32	117 / 1155
skin	39%	238.28	709 / 1809	41%	8.01	192 / 472
blood vessel	69%	115.11	919 / 1335	0%	0	0 / 0
heart	63%	77.36	539 / 861	0%	0	0 / 0
peripheral blood	51%	60.16	476 / 929	0%	0	0 / 0
adrenal gland	20%	20.09	52 / 258	24%	0.89	55 / 230
kidney	34%	30.66	30 / 89	4%	0.20	37 / 901
uterus	24%	29.75	40 / 170	8%	0.49	36 / 459
thymus	20%	13.58	128 / 653	11%	0.23	67 / 605
breast	27%	23.68	122 / 459	2%	0.09	25 / 1118
ovary	23%	18.02	41 / 180	0%	0.01	1 / 430
adipose	22%	19.48	260 / 1204	0%	0	0 / 0
liver	10%	6.65	22 / 226	11%	0.31	43 / 406
brain	10%	6.74	268 / 2642	9%	0.26	61 / 705
spleen	14%	7.47	34 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.19	5 / 80
tonsil	0%	0	0 / 0	2%	0.21	1 / 45
muscle	0%	0.34	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008356	Biological process	asymmetric cell division
GO_0000132	Biological process	establishment of mitotic spindle orientation
GO_0007399	Biological process	nervous system development
GO_0009786	Biological process	regulation of asymmetric cell division
GO_0030154	Biological process	cell differentiation
GO_0045176	Biological process	apical protein localization
GO_0031647	Biological process	regulation of protein stability
GO_0032991	Cellular component	protein-containing complex
GO_0005938	Cellular component	cell cortex
GO_0005886	Cellular component	plasma membrane
GO_0045179	Cellular component	apical cortex
GO_0030674	Molecular function	protein-macromolecule adaptor activity
GO_0008093	Molecular function	cytoskeletal anchor activity
GO_0019904	Molecular function	protein domain specific binding
GO_0005515	Molecular function	protein binding

Gene name	INSC
Protein name	Protein inscuteable homolog INSC spindle orientation adaptor protein
Synonyms
Description	FUNCTION: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex . Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium (By similarity). .
Accessions	ENST00000424273.5 ENST00000379556.8 [Q1MX18-2] ENST00000379554.7 [Q1MX18-1] ENST00000525218.1 [Q1MX18-4] ENST00000528567.5 [Q1MX18-6] A0A0A0MSI1 Q1MX18 ENST00000530161.5 [Q1MX18-2]

INSC report