Insufficient scRNA-seq data for expression of SRPK3 at single-cell level.
Insufficient scRNA-seq data for expression of SRPK3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 98% | 708.64 | 241 / 245 | 90% | 3.52 | 451 / 502 |
brain | 83% | 512.73 | 2184 / 2642 | 89% | 3.43 | 626 / 705 |
bladder | 95% | 563.52 | 20 / 21 | 67% | 2.33 | 336 / 504 |
intestine | 88% | 790.90 | 850 / 966 | 68% | 2.37 | 357 / 527 |
uterus | 90% | 467.38 | 153 / 170 | 64% | 5.71 | 293 / 459 |
stomach | 61% | 282.31 | 220 / 359 | 59% | 2.37 | 170 / 286 |
adrenal gland | 26% | 74.43 | 68 / 258 | 80% | 6.67 | 184 / 230 |
muscle | 100% | 5688.79 | 803 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 2154.83 | 849 / 861 | 0% | 0 | 0 / 0 |
esophagus | 51% | 234.33 | 735 / 1445 | 46% | 1.19 | 85 / 183 |
blood vessel | 95% | 747.58 | 1268 / 1335 | 0% | 0 | 0 / 0 |
breast | 31% | 77.97 | 143 / 459 | 60% | 3.63 | 671 / 1118 |
ovary | 44% | 118.64 | 79 / 180 | 45% | 1.56 | 195 / 430 |
lung | 25% | 59.94 | 145 / 578 | 59% | 2.62 | 680 / 1155 |
pancreas | 3% | 7.65 | 11 / 328 | 57% | 1.52 | 101 / 178 |
skin | 28% | 70.95 | 505 / 1809 | 25% | 0.67 | 117 / 472 |
spleen | 45% | 106.88 | 108 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 41% | 0.75 | 12 / 29 |
tonsil | 0% | 0 | 0 / 0 | 29% | 0.87 | 13 / 45 |
eye | 0% | 0 | 0 / 0 | 24% | 0.35 | 19 / 80 |
kidney | 11% | 28.22 | 10 / 89 | 10% | 0.24 | 89 / 901 |
adipose | 20% | 51.22 | 240 / 1204 | 0% | 0 | 0 / 0 |
liver | 4% | 9.73 | 10 / 226 | 10% | 0.29 | 41 / 406 |
thymus | 5% | 13.95 | 30 / 653 | 9% | 0.26 | 56 / 605 |
peripheral blood | 2% | 7.63 | 22 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050684 | Biological process | regulation of mRNA processing |
GO_0060537 | Biological process | muscle tissue development |
GO_0018105 | Biological process | peptidyl-serine phosphorylation |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0000245 | Biological process | spliceosomal complex assembly |
GO_0007519 | Biological process | skeletal muscle tissue development |
GO_0030154 | Biological process | cell differentiation |
GO_0005575 | Cellular component | cellular_component |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | SRPK3 |
Protein name | non-specific serine/threonine protein kinase (EC 2.7.11.1) SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23) |
Synonyms | hCG_39220 STK23 MSSK1 |
Description | FUNCTION: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity). . |
Accessions | ENST00000370101.8 [Q9UPE1-1] ENST00000370104.5 [Q9UPE1-4] ENST00000370108.7 H7C1T4 ENST00000489426.5 ENST00000430541.5 A8MPP7 ENST00000370100.5 ENST00000458681.1 Q9UPE1 ENST00000393786.7 [Q9UPE1-3] H7C2I2 E7ETV6 A8MPY5 |